Steps for the use of analgesics in patients with hemophilic arthropathy
| Guideline . | Medication . | Administration . |
|---|---|---|
| 1 | Paracetamol | 500-1000 mg orally, ≤ 6×/d is the initial medication of choice; if not effective, go to Guideline 2. |
| 2 | Celecoxib (COX2 inhibitor) | 100-200 mg orally, 1-2×/d; if not effective, go to Guideline 3. |
| 3 | Paracetamol + codeine orParacetamol + tramadol | 10-20 mg orally, no more than 6×/d, or50-100 mg orally, 3-4×/d; if not effective, go to Guideline 4. |
| 4 | Morphine | Use a slow-release product, starting with 20 mg 2×/d, with an escape to a rapid-release product 10 mg 4×/d. Increase the slow-release product if the rapid-release product is used more than 4×/d. |
| Guideline . | Medication . | Administration . |
|---|---|---|
| 1 | Paracetamol | 500-1000 mg orally, ≤ 6×/d is the initial medication of choice; if not effective, go to Guideline 2. |
| 2 | Celecoxib (COX2 inhibitor) | 100-200 mg orally, 1-2×/d; if not effective, go to Guideline 3. |
| 3 | Paracetamol + codeine orParacetamol + tramadol | 10-20 mg orally, no more than 6×/d, or50-100 mg orally, 3-4×/d; if not effective, go to Guideline 4. |
| 4 | Morphine | Use a slow-release product, starting with 20 mg 2×/d, with an escape to a rapid-release product 10 mg 4×/d. Increase the slow-release product if the rapid-release product is used more than 4×/d. |