Clinical characteristics of patients with T-cell compared with B-cell acute lymphoblastic leukemia and overall survival in T-cell patients
| . | T-cell ALL, n (%) . | B-cell ALL, n (%)* . | P . | 5-year overall survival in T-cell ALL, percentage (95% CI) . | P . |
|---|---|---|---|---|---|
| Group | |||||
| ECOG | 146 (41) | 389 (34) | 47 (39-56) | ||
| NRCI | 210 (59) | 758 (66) | 48 (41-55) | ||
| P | .01† | > .1‡ | |||
| Age, y | |||||
| Younger than 20 | 55 (15) | 256 (22) | 53 (40-67) | ||
| 20-29 | 136 (38) | 311 (27) | 52 (43-60) | ||
| 30-39 | 85 (24) | 216 (19) | 46 (35-57) | ||
| 40-49 | 46 (13) | 203 (18) | 47 (32-63) | ||
| 50 or older | 34 (10) | 161 (14) | 27 (11-43) | ||
| P | < .001†/.06§ | .009‖ | |||
| 35 or younger | 244 (69) | 704 (61) | 52 (46-58) | ||
| Older than 35 | 112 (31) | 443 (39) | 38 (29-48) | ||
| P | .01† | .004‡ | |||
| Sex | |||||
| Male | 260 (73) | 680 (59) | 50 (44-57) | ||
| Female | 96 (27) | 467 (41) | 41 (31-51) | ||
| P | < .001† | .05‡ | |||
| Diagnostic WBC, ×109/L | |||||
| Less than 50 | 203 (58) | 920 (81) | 49 (42-56) | ||
| 50-99 | 54 (15) | 96 (8) | 56 (42-69) | ||
| 100 or more | 96 (27) | 125 (11) | 41 (31-51) | ||
| P | < .001§ | .09‖ (< 100 vs ≥ 100, P = .03‡) | |||
| CNS involvement | |||||
| Yes | 32 (9) | 46 (4) | 47 (29-64) | ||
| No/unknown | 324 (91) | 1101 (96) | 48 (42-54) | ||
| P | < .001†/ < .001¶ | > .1‡/> .1 |
| . | T-cell ALL, n (%) . | B-cell ALL, n (%)* . | P . | 5-year overall survival in T-cell ALL, percentage (95% CI) . | P . |
|---|---|---|---|---|---|
| Group | |||||
| ECOG | 146 (41) | 389 (34) | 47 (39-56) | ||
| NRCI | 210 (59) | 758 (66) | 48 (41-55) | ||
| P | .01† | > .1‡ | |||
| Age, y | |||||
| Younger than 20 | 55 (15) | 256 (22) | 53 (40-67) | ||
| 20-29 | 136 (38) | 311 (27) | 52 (43-60) | ||
| 30-39 | 85 (24) | 216 (19) | 46 (35-57) | ||
| 40-49 | 46 (13) | 203 (18) | 47 (32-63) | ||
| 50 or older | 34 (10) | 161 (14) | 27 (11-43) | ||
| P | < .001†/.06§ | .009‖ | |||
| 35 or younger | 244 (69) | 704 (61) | 52 (46-58) | ||
| Older than 35 | 112 (31) | 443 (39) | 38 (29-48) | ||
| P | .01† | .004‡ | |||
| Sex | |||||
| Male | 260 (73) | 680 (59) | 50 (44-57) | ||
| Female | 96 (27) | 467 (41) | 41 (31-51) | ||
| P | < .001† | .05‡ | |||
| Diagnostic WBC, ×109/L | |||||
| Less than 50 | 203 (58) | 920 (81) | 49 (42-56) | ||
| 50-99 | 54 (15) | 96 (8) | 56 (42-69) | ||
| 100 or more | 96 (27) | 125 (11) | 41 (31-51) | ||
| P | < .001§ | .09‖ (< 100 vs ≥ 100, P = .03‡) | |||
| CNS involvement | |||||
| Yes | 32 (9) | 46 (4) | 47 (29-64) | ||
| No/unknown | 324 (91) | 1101 (96) | 48 (42-54) | ||
| P | < .001†/ < .001¶ | > .1‡/> .1 |