Evaluation of steady-state hematopoiesis in Stat5f/f:Mx1-Cre mice
| . | Stat5f/f . | Stat5f/f:Mx1-Cre . | P . |
|---|---|---|---|
| Red blood cells, × 106/μL | 9.08 ± 0.48 | 5.94 ± 1.28 | < .001 |
| Hemoglobin, g/dL | 13.3 ± 0.6 | 8.0 ± 0.9 | < .001 |
| Hematocrit, percentage | 41.9 ± 2.0 | 25.9 ± 3.4 | < .001 |
| White blood cells, × 103/μL | 8.70 ± 1.61 | 3.05 ± 1.06 | < .001 |
| Neutrophils, × 103/μL | 1.54 ± 0.35 | 0.71 ± 0.35 | < .001 |
| Lymphocytes, × 103/μL | 6.80 ± 1.41 | 2.11 ± 0.78 | < .001 |
| Monocytes, × 103/μL/μL | 0.30 ± 0.09 | 0.17 ± 0.09 | < .001 |
| Eosinophils, × 103/μL | 0.05 ± 0.03 | 0.04 ± 0.03 | NS |
| Basophils, × 103/μL | 0.01 ± 0.01 | 0.01 ± 0.01 | NS |
| Platelets, × 103/μL | 850 ± 200 | 744 ± 164 | NS |
| . | Stat5f/f . | Stat5f/f:Mx1-Cre . | P . |
|---|---|---|---|
| Red blood cells, × 106/μL | 9.08 ± 0.48 | 5.94 ± 1.28 | < .001 |
| Hemoglobin, g/dL | 13.3 ± 0.6 | 8.0 ± 0.9 | < .001 |
| Hematocrit, percentage | 41.9 ± 2.0 | 25.9 ± 3.4 | < .001 |
| White blood cells, × 103/μL | 8.70 ± 1.61 | 3.05 ± 1.06 | < .001 |
| Neutrophils, × 103/μL | 1.54 ± 0.35 | 0.71 ± 0.35 | < .001 |
| Lymphocytes, × 103/μL | 6.80 ± 1.41 | 2.11 ± 0.78 | < .001 |
| Monocytes, × 103/μL/μL | 0.30 ± 0.09 | 0.17 ± 0.09 | < .001 |
| Eosinophils, × 103/μL | 0.05 ± 0.03 | 0.04 ± 0.03 | NS |
| Basophils, × 103/μL | 0.01 ± 0.01 | 0.01 ± 0.01 | NS |
| Platelets, × 103/μL | 850 ± 200 | 744 ± 164 | NS |
Data are mean ± SD of peripheral blood count analyses of Stat5f/f (n = 22) and Stat5f/f:Mx1-Cre mice (n = 23) at the age of 9 to 14 weeks. Peripheral blood was assayed at least 3 weeks after PolyIC injection.
NS indicates no significant difference.