Table 1 Bleeding pattern, treatment, and... | American Society of Hematology

Table 1

Bleeding pattern, treatment, and outcome according to hemophilia type in patients with severe hemophilia treated at the van Creveldkliniek

Characteristic	Hemophilia A	Hemophilia B	P*
No. of patients	252 (89%)	30 (11%)	—
Age at last evaluation, y	27.7 (2.8-51.7)	32.3 (2.5-52.8)	.738
Arthroplasty	78 (31%)	9 (30%)	.915
Age at 1st treatment, y	1.1 (0.2-2.7)	1.3 (0.6-2.9)	.065
Age at 1st joint bleed, y	1.9 (0.5-5.9)	2.4 (0.9-5.5)	.652
Prophylaxis†	194 (77%)	22 (73%)	.655
Annual joint bleeding frequency	4.3 (0.3-16.3)	3.8 (0.4-17.8)	.379
Annual factor use‡	1560 (286-3644)	1260 (302-5826)	.559

Characteristic	Hemophilia A	Hemophilia B	P*
No. of patients	252 (89%)	30 (11%)	—
Age at last evaluation, y	27.7 (2.8-51.7)	32.3 (2.5-52.8)	.738
Arthroplasty	78 (31%)	9 (30%)	.915
Age at 1st treatment, y	1.1 (0.2-2.7)	1.3 (0.6-2.9)	.065
Age at 1st joint bleed, y	1.9 (0.5-5.9)	2.4 (0.9-5.5)	.652
Prophylaxis†	194 (77%)	22 (73%)	.655
Annual joint bleeding frequency	4.3 (0.3-16.3)	3.8 (0.4-17.8)	.379
Annual factor use‡	1560 (286-3644)	1260 (302-5826)	.559

Values are reported as numbers (percentages) or medians (5th-95th percentiles).

Continuous variables were tested with Mann-Whitney test, categorical variables by χ² test.

Use of prophylaxis was calculated over the last 3 years of treatment.

Per kilogram of body weight.