Table 4

Results of multivariable analysis of significant exposures for risk of adolescent/young adult Hodgkin lymphoma in disease-discordant twin pairs diagnosed at 50 years or younger

ExposureOR*95% CIP
Appendectomy 4.3 1.9-10.0 .001 
Eczema 4.2 1.2-14.8 .025 
Smoked cigarettes, ever/never 2.2 1.0-5.0 .054 
Relatively more behaviors resulting in early oral exposures§ 0.1 0.0-0.5 .004 
ExposureOR*95% CIP
Appendectomy 4.3 1.9-10.0 .001 
Eczema 4.2 1.2-14.8 .025 
Smoked cigarettes, ever/never 2.2 1.0-5.0 .054 
Relatively more behaviors resulting in early oral exposures§ 0.1 0.0-0.5 .004 
*

Odds ratio estimated using multivariable conditional logistic regression adjusting for all variables above in the model simultaneously.

Confidence interval estimated using conditional logistic regression.

P value estimated from the Mantel-Haenszel χ2 test.

§

Sucked thumb, finger, or pacifier more and put more things in mouth.

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