Relative differences in childhood behaviors associated with transmission of infection and the risk of young adult Hodgkin lymphoma diagnosed between 13 and 50 years of age in disease-discordant twin pairs
| Relative differences in childhood behaviors: which twin … ? . | Ratio of exposure, discordant pairs* . | Odds ratio† . | 95% CI‡ . | P§ . |
|---|---|---|---|---|
| Sucked pacifier/thumb/fingers more as an infant/young child?‖ | ||||
| Total¶ | 18/34 | 0.5 | 0.3-0.9 | .03 |
| Double respondent# | 11/20 | 0.6 | 0.3-1.1 | .11 |
| Put more things in mouth as an infant/young child?‖ | ||||
| Total¶ | 10/30 | 0.3 | 0.2-0.7 | .003 |
| Double respondent# | 6/17 | 0.4 | 0.1-0.9 | .03 |
| Sucked more and put more things in mouth as infant/child? | ||||
| Total¶ | 4/20 | 0.2 | 0.1-0.6 | .003 |
| Double respondent# | 4/13 | 0.3 | 0.1-0.9 | .04 |
| Bit their nails more? | ||||
| Total¶ | 33/42 | 0.8 | 0.5-1.2 | .30 |
| Double respondent# | 16/21 | 0.8 | 0.4-1.5 | .41 |
| Kissed people more as children? | ||||
| Total¶ | 22/32 | 0.7 | 0.4-1.2 | .18 |
| Double respondent# | 11/13 | 0.8 | 0.4-1.9 | .68 |
| Had more contact with family pets? | ||||
| Total¶ | 25/22 | 1.1 | 0.6-2.0 | .66 |
| Double respondent# | 13/8 | 1.6 | 0.7-3.9 | .28 |
| Relative differences in childhood behaviors: which twin … ? . | Ratio of exposure, discordant pairs* . | Odds ratio† . | 95% CI‡ . | P§ . |
|---|---|---|---|---|
| Sucked pacifier/thumb/fingers more as an infant/young child?‖ | ||||
| Total¶ | 18/34 | 0.5 | 0.3-0.9 | .03 |
| Double respondent# | 11/20 | 0.6 | 0.3-1.1 | .11 |
| Put more things in mouth as an infant/young child?‖ | ||||
| Total¶ | 10/30 | 0.3 | 0.2-0.7 | .003 |
| Double respondent# | 6/17 | 0.4 | 0.1-0.9 | .03 |
| Sucked more and put more things in mouth as infant/child? | ||||
| Total¶ | 4/20 | 0.2 | 0.1-0.6 | .003 |
| Double respondent# | 4/13 | 0.3 | 0.1-0.9 | .04 |
| Bit their nails more? | ||||
| Total¶ | 33/42 | 0.8 | 0.5-1.2 | .30 |
| Double respondent# | 16/21 | 0.8 | 0.4-1.5 | .41 |
| Kissed people more as children? | ||||
| Total¶ | 22/32 | 0.7 | 0.4-1.2 | .18 |
| Double respondent# | 11/13 | 0.8 | 0.4-1.9 | .68 |
| Had more contact with family pets? | ||||
| Total¶ | 25/22 | 1.1 | 0.6-2.0 | .66 |
| Double respondent# | 13/8 | 1.6 | 0.7-3.9 | .28 |
Total number of twin pairs in which case-twin was exposed and the unaffected cotwin was unexposed/total number of twin pairs in which unaffected cotwin was exposed and the case-twin was unexposed.
Odds ratio estimated using conditional logistic regression using SAS Version 9.1.
Confidence interval estimated using conditional logistic regression.
P value estimated from the Wald test.
Lower 95% confidence interval for kappa 0.70 or higher.
Eighty-eight total respondent pairs = double- and single-respondent twin pairs. Single-respondent pairs are those in whom only 1 member of the pair sent a questionnaire but answered questions about their twin's exposures (eg, proxy report for the nonresponding twin).
Ninety-three double-respondent pairs. Double-respondent pair = both members of the twin pair sent back a questionnaire; answers are based on self-report.