Comparison of patients with an ICH to the case controls
| . | ICH cases, n = 40 (%) . | Case controls, n = 80 (%) . |
|---|---|---|
| Sex | ||
| Female | 22 (55) | 35 (44) |
| Male | 18 (45) | 45 (56) |
| ITP duration | ||
| Acute ITP less than 6 mo | 28 (70) | 66 (82.5) |
| Chronic ITP 6 mo or more | 12 (30) | 14 (17.5) |
| Platelet counts | ||
| Median, platelets/μL | 5000 | 8000 |
| Range, platelets/μL | 1 to 61 000 | 1 to 28 000 |
| Platelet count less than 20 000/μL | 36 (90) | 68 (85) |
| Platelet count less than 10 000/μL | 30 (75) | 47 (59) |
| Age | ||
| Age range | 3 mo-17 y | 2 mo-17 y |
| Number of patients younger than 10 y old | 23 (58) | 53 (66) |
| Number of patients 10 y or older | 17 (43) | 27 (34) |
| NSAID use* | ||
| Number of patients reporting recent NSAID use | 3 (7.5) | 1 (1.25) |
| Head trauma* | 13 (33) | 1 (1) |
| Bleeding symptoms* | ||
| No bleeding | 3 (7.5) | 4 (5) |
| Any bleeding | 37 (92.5) | 76 (95) |
| Petechiae | 25 (63) | 64 (80) |
| Ecchymosis | 30 (75) | 60 (75) |
| Bleeding other than petechiae and ecchymosis | 25 (63) | 35 (44) |
| Wet purpura | 11 (27.5) | 15 (19) |
| Epistaxis | 15 (37.5) | 19 (24) |
| Gum bleeding | 9 (22.5) | 8 (10) |
| GI bleeding | 7 (17.5) | 5 (6) |
| U bleeding | 9 (22.5) | 0 (0) |
| GYN bleeding | 0 | 3 (4) |
| Head trauma and bleeding symptoms | ||
| Both head trauma and bleeding other than petechiae and ecchymosis | 4 (10) | 0 (0) |
| Head trauma and no bleeding other than petechiae and ecchymosis | 9 (23) | 1 (1) |
| No head trauma but bleeding other than petechiae and ecchymosis | 20 (51) | 35 (44) |
| No head trauma and no bleeding other than petechiae and ecchymosis | 6 (15) | 44 (55) |
| . | ICH cases, n = 40 (%) . | Case controls, n = 80 (%) . |
|---|---|---|
| Sex | ||
| Female | 22 (55) | 35 (44) |
| Male | 18 (45) | 45 (56) |
| ITP duration | ||
| Acute ITP less than 6 mo | 28 (70) | 66 (82.5) |
| Chronic ITP 6 mo or more | 12 (30) | 14 (17.5) |
| Platelet counts | ||
| Median, platelets/μL | 5000 | 8000 |
| Range, platelets/μL | 1 to 61 000 | 1 to 28 000 |
| Platelet count less than 20 000/μL | 36 (90) | 68 (85) |
| Platelet count less than 10 000/μL | 30 (75) | 47 (59) |
| Age | ||
| Age range | 3 mo-17 y | 2 mo-17 y |
| Number of patients younger than 10 y old | 23 (58) | 53 (66) |
| Number of patients 10 y or older | 17 (43) | 27 (34) |
| NSAID use* | ||
| Number of patients reporting recent NSAID use | 3 (7.5) | 1 (1.25) |
| Head trauma* | 13 (33) | 1 (1) |
| Bleeding symptoms* | ||
| No bleeding | 3 (7.5) | 4 (5) |
| Any bleeding | 37 (92.5) | 76 (95) |
| Petechiae | 25 (63) | 64 (80) |
| Ecchymosis | 30 (75) | 60 (75) |
| Bleeding other than petechiae and ecchymosis | 25 (63) | 35 (44) |
| Wet purpura | 11 (27.5) | 15 (19) |
| Epistaxis | 15 (37.5) | 19 (24) |
| Gum bleeding | 9 (22.5) | 8 (10) |
| GI bleeding | 7 (17.5) | 5 (6) |
| U bleeding | 9 (22.5) | 0 (0) |
| GYN bleeding | 0 | 3 (4) |
| Head trauma and bleeding symptoms | ||
| Both head trauma and bleeding other than petechiae and ecchymosis | 4 (10) | 0 (0) |
| Head trauma and no bleeding other than petechiae and ecchymosis | 9 (23) | 1 (1) |
| No head trauma but bleeding other than petechiae and ecchymosis | 20 (51) | 35 (44) |
| No head trauma and no bleeding other than petechiae and ecchymosis | 6 (15) | 44 (55) |
GI indicates gastrointestinal; U, urinary; and GYN, gynecological/vaginal.
Data for bleeding symptoms, NSAID use, and head trauma were considered negative if no specific response was provided on the questionnaire.