Table 2

Summary of protein expression and CRP-mediated events in WASp KO, WIP KOlow, and WIP KOhigh platelets

Protein expression/eventWASp KO plateletsWIP KOlow plateletsWIP KOhigh platelets
WASp expression 
WIP expression 55 
PLC-γ2 phosphorylation 100 45-55 0-25 
Calcium mobilization 115-140 100 50-70 
P-selectin expression 110-120 100 60-80 
αIIbβ3 activation 100-110 55-100 25-45 
Actin assembly 110-125 95-125 35-75 
Protein expression/eventWASp KO plateletsWIP KOlow plateletsWIP KOhigh platelets
WASp expression 
WIP expression 55 
PLC-γ2 phosphorylation 100 45-55 0-25 
Calcium mobilization 115-140 100 50-70 
P-selectin expression 110-120 100 60-80 
αIIbβ3 activation 100-110 55-100 25-45 
Actin assembly 110-125 95-125 35-75 

Values are percentages relative to protein expression and CRP-mediated events in WT platelets.

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