Table 5

miRNAs that are differentially expressed in CLL 17p-aggressive compared with CLL 17p-indolent groups

miRNAFold change*P
Down-regulated   
    miR-29b 0.53 <.001 
    miR-181b 0.59 .004 
    miR-181c 0.1 .012 
    miR-181d 0.11 .016 
    miR-342-3p 0.66 .017 
    miR-223 0.44 .024 
    miR-181a 0.15 .028 
    miR-29c 0.56 .03 
    miR-29b-1* 0.74 .04 
    miR-367 0.16 .049 
Up-regulated   
    miR-130b* 1.44 .011 
    miR-129-3p 11.63 .013 
    miR-632 1.15 .021 
    miR-768-5p 1.36 .021 
    miR-638 1.58 .028 
    miR-453 7.72 .047 
miRNAFold change*P
Down-regulated   
    miR-29b 0.53 <.001 
    miR-181b 0.59 .004 
    miR-181c 0.1 .012 
    miR-181d 0.11 .016 
    miR-342-3p 0.66 .017 
    miR-223 0.44 .024 
    miR-181a 0.15 .028 
    miR-29c 0.56 .03 
    miR-29b-1* 0.74 .04 
    miR-367 0.16 .049 
Up-regulated   
    miR-130b* 1.44 .011 
    miR-129-3p 11.63 .013 
    miR-632 1.15 .021 
    miR-768-5p 1.36 .021 
    miR-638 1.58 .028 
    miR-453 7.72 .047 

CLL indicates chronic lymphoid leukemia; miRNA, microRNAs.

*

Fold change is the fold-ratio of geometric means of miRNA expressions from 17p-aggressive and 17p-indolent subgroups.

P and fold change are the results of the class comparison analysis within Biometric Research Branch Array Tool.

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