Table 2

Gene expression profiles of CD34+ cells

Affymetrix IDGeneMapPAverage ratio
RARS-TRARS
232363_at PSIP1 (LEDGF) 9p22.2 < .001 1.20 0.71 
229712_at SNAPC3 9p22.2 < .002 1.39 0.83 
219221_at FLJ35036 3q23 < .002 2.18 1.14 
210926_at ACTB 7p15-p12 < .002 0.79 1.30 
224920_x_at MYADM 19q13.42 < .002 0.69 1.05 
1557905_s_at CD44 11p13 < .002 0.58 1.08 
243910_x_at TIP120A 12q14 < .002 1.37 0.70 
219007_at NUP43 6q24.3 < .002 1.58 0.98 
210916_s_at CD44 11p13 < .002 0.61 1.06 
204461_x_at RAD1 5p13.2 < .002 1.32 0.87 
Affymetrix IDGeneMapPAverage ratio
RARS-TRARS
232363_at PSIP1 (LEDGF) 9p22.2 < .001 1.20 0.71 
229712_at SNAPC3 9p22.2 < .002 1.39 0.83 
219221_at FLJ35036 3q23 < .002 2.18 1.14 
210926_at ACTB 7p15-p12 < .002 0.79 1.30 
224920_x_at MYADM 19q13.42 < .002 0.69 1.05 
1557905_s_at CD44 11p13 < .002 0.58 1.08 
243910_x_at TIP120A 12q14 < .002 1.37 0.70 
219007_at NUP43 6q24.3 < .002 1.58 0.98 
210916_s_at CD44 11p13 < .002 0.61 1.06 
204461_x_at RAD1 5p13.2 < .002 1.32 0.87 

The 10 most significant differentially expressed genes between patients with RARS-T and with RARS are listed.

RARS-T indicates refractory anemia with ringed sideroblasts associated with marked thrombocytosis; and RARS, refractory anemia with ringed sideroblasts.

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