Mean recordings of regional cerebral blood flow
Mouse/treatment . | Figure . | n . | MCAO, % before ischemia . | Reperfusion, % before ischemia . |
---|---|---|---|---|
WT | 1 | 13 | 12.1 | 79.9 |
VWF+/− | 1 | 13 | 12.5 | 86.6 |
VWF−/− | 1 | 10 | 15.6 | 77.9 |
WT | 2 | 13 | 13.9 | 84.7 |
ADAMTS13−/− | 2 | 15 | 13.4 | 87.9 |
VWF−/−ADAMTS13−/− | 2 | 6 | 12.7 | 78.0 |
WT | 3 | 9 | 11.8 | 82.0 |
r-hu ADAMTS13 (HEK) | 3 | 9 | 13 | 75.7 |
WT | 3 | 8 | 12.4 | 78.8 |
r-hu ADAMTS13 (CHO) | 3 | 9 | 10.7 | 89.2 |
Mouse/treatment . | Figure . | n . | MCAO, % before ischemia . | Reperfusion, % before ischemia . |
---|---|---|---|---|
WT | 1 | 13 | 12.1 | 79.9 |
VWF+/− | 1 | 13 | 12.5 | 86.6 |
VWF−/− | 1 | 10 | 15.6 | 77.9 |
WT | 2 | 13 | 13.9 | 84.7 |
ADAMTS13−/− | 2 | 15 | 13.4 | 87.9 |
VWF−/−ADAMTS13−/− | 2 | 6 | 12.7 | 78.0 |
WT | 3 | 9 | 11.8 | 82.0 |
r-hu ADAMTS13 (HEK) | 3 | 9 | 13 | 75.7 |
WT | 3 | 8 | 12.4 | 78.8 |
r-hu ADAMTS13 (CHO) | 3 | 9 | 10.7 | 89.2 |
Laser-Doppler flow was continuously recorded during induction of focal cerebral ischemia and reperfusion. No major differences were observed between the groups of animals.