Table 1

Mean recordings of regional cerebral blood flow

Mouse/treatmentFigurenMCAO, % before ischemiaReperfusion, % before ischemia
WT 13 12.1 79.9 
VWF+/− 13 12.5 86.6 
VWF−/− 10 15.6 77.9 
WT 13 13.9 84.7 
ADAMTS13−/− 15 13.4 87.9 
VWF−/−ADAMTS13−/− 12.7 78.0 
WT 11.8 82.0 
r-hu ADAMTS13 (HEK) 13 75.7 
WT 12.4 78.8 
r-hu ADAMTS13 (CHO) 10.7 89.2 
Mouse/treatmentFigurenMCAO, % before ischemiaReperfusion, % before ischemia
WT 13 12.1 79.9 
VWF+/− 13 12.5 86.6 
VWF−/− 10 15.6 77.9 
WT 13 13.9 84.7 
ADAMTS13−/− 15 13.4 87.9 
VWF−/−ADAMTS13−/− 12.7 78.0 
WT 11.8 82.0 
r-hu ADAMTS13 (HEK) 13 75.7 
WT 12.4 78.8 
r-hu ADAMTS13 (CHO) 10.7 89.2 

Laser-Doppler flow was continuously recorded during induction of focal cerebral ischemia and reperfusion. No major differences were observed between the groups of animals.