Table 2 ADA-SCID patients on ERT with... | American Society of Hematology

Table 2

ADA-SCID patients on ERT with PEG-ADA display reduced growth

	Age at last follow-up, y	PEG-ADA, y	Percentile height, Z-score	RANKL, pg/mL	OPG, pg/mL	RANKL/OPG, × 10²
Patient no. 6	5.6	5	−1.69	0	78.1	0
Patient no. 7	1.5	1	−2.06	0	120.6	0
Patient no. 8	1.4	1	−0.29	1.61	153.2	1.05
Patient no. 9	1.3	1	1.29	0	145.2	0
Patient no. 10	6.2	6	−0.38	2.85	18.4	15.48
Patient no. 11	2.5	1	−2.14	2.57	173.8	1.48
Patient no. 12	12.5	10	−3.61	0	93.3	0
Patient no. 13	22.5	21	−0.93	0	167.5	0
Patient no. 14	19	17	−1.98	0	135.3	0
ND 1-15 years of age (n = 14), mean (SEM)				8.06 (1.6)	106.9 (5.6)	8.4 (1.7)
P				.004	.504	.033

	Age at last follow-up, y	PEG-ADA, y	Percentile height, Z-score	RANKL, pg/mL	OPG, pg/mL	RANKL/OPG, × 10²
Patient no. 6	5.6	5	−1.69	0	78.1	0
Patient no. 7	1.5	1	−2.06	0	120.6	0
Patient no. 8	1.4	1	−0.29	1.61	153.2	1.05
Patient no. 9	1.3	1	1.29	0	145.2	0
Patient no. 10	6.2	6	−0.38	2.85	18.4	15.48
Patient no. 11	2.5	1	−2.14	2.57	173.8	1.48
Patient no. 12	12.5	10	−3.61	0	93.3	0
Patient no. 13	22.5	21	−0.93	0	167.5	0
Patient no. 14	19	17	−1.98	0	135.3	0
ND 1-15 years of age (n = 14), mean (SEM)				8.06 (1.6)	106.9 (5.6)	8.4 (1.7)
P				.004	.504	.033