Table 1

ADA-SCID patients naive for therapy display significantly reduced growth

Age, yPercentile height, Z-scoreRANKL, pg/mLOPG, pg/mLRANKL/OPG, × 102
Patient no. 1 −1.66 1.42 181.9 0.78 
Patient no. 2 1.9 −3.91 1.03 129.6 0.79 
Patient no. 3 1.8 −1.83 181.9 
Patient no. 4 1.6 −1.90 145.2 
Patient no. 5 0.5 −2.21 3.08 257.3 1.19 
ND 1-5 years of age (n = 10), mean (SEM)   11.49 (3) 104.1 (7) 13.4 (5) 
P   .005 .003 .011 
Age, yPercentile height, Z-scoreRANKL, pg/mLOPG, pg/mLRANKL/OPG, × 102
Patient no. 1 −1.66 1.42 181.9 0.78 
Patient no. 2 1.9 −3.91 1.03 129.6 0.79 
Patient no. 3 1.8 −1.83 181.9 
Patient no. 4 1.6 −1.90 145.2 
Patient no. 5 0.5 −2.21 3.08 257.3 1.19 
ND 1-5 years of age (n = 10), mean (SEM)   11.49 (3) 104.1 (7) 13.4 (5) 
P   .005 .003 .011 

ND indicates normal donor.

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