Frequencies, significance for monoallelic and biallelic TNFRSF13B variants in patients and control group: presence of variants in healthy first-degree relatives (HFDR)
| Genotype . | CVID . | Controls . | P . | HFDR . |
|---|---|---|---|---|
| p.C104R/p.C104R | 6/120 | 0/198 | .006 | 3 |
| p.C104/wt | 2/120 | 5/198 | n.s. | 21 |
| p.C104R/A181E | 1/120 | 0/198 | n.s. | 1 |
| p.L171R/p.L171R | 1/120 | 0/198 | n.s. | n.a. |
| p.L171R/wt | 1/120 | 0/198 | n.s. | n.a. |
| p.E140K/wt | 1/120 | 0/198 | n.s. | n.a. |
| p.C89Y/wt | 1/120 | 0/198 | n.s. | n.a. |
| p.E117G/wt | 1/120 | 0/198 | n.s. | n.a. |
| p.A181E/wt | 0/120 | 0/198 | n.s. | 3 |
| Genotype . | CVID . | Controls . | P . | HFDR . |
|---|---|---|---|---|
| p.C104R/p.C104R | 6/120 | 0/198 | .006 | 3 |
| p.C104/wt | 2/120 | 5/198 | n.s. | 21 |
| p.C104R/A181E | 1/120 | 0/198 | n.s. | 1 |
| p.L171R/p.L171R | 1/120 | 0/198 | n.s. | n.a. |
| p.L171R/wt | 1/120 | 0/198 | n.s. | n.a. |
| p.E140K/wt | 1/120 | 0/198 | n.s. | n.a. |
| p.C89Y/wt | 1/120 | 0/198 | n.s. | n.a. |
| p.E117G/wt | 1/120 | 0/198 | n.s. | n.a. |
| p.A181E/wt | 0/120 | 0/198 | n.s. | 3 |
χ2 test compared CVID and control group.
n.s. indicates not significant; and n.a., not available.