Gene products identified by SEREX in MGUS patients
| Gene product . | Gene ID . | Gene chromosomal locus . | Cellular localization . | Molecular function . | Cellular process . |
|---|---|---|---|---|---|
| OFD1 | 8481 | Xp22.2-p22.3 | Basal body/centrosome, cytosol | Unknown | Ciliogenesis |
| ZNF292 | 23036 | 6q15 | Nucleus | DNA binding | Transcription regulation DNA-dependent |
| AKAP11 | 11215 | 13q14.11 | Centrosome, cytosol | PKA binding, PP1-binding | Protein-kinase cascade |
| GPATCH4 | 54865 | 1q22 | Intracellular | Nucleic acid binding | Unknown |
| SON | 6651 | 21q22.1-22.2; 21q22.11 | Intracellular, nucleus | Nucleic acid binding, protein binding | Antiapoptosis |
| FAM50A | 9130 | Xq28 | Nucleus | Unknown | Spermatogenesis |
| SSSCA1 | 10534 | 11q13.1 | Unknown | Protein binding | Cell cycle, cell division, mitosis |
| IFT57/HIPPI | 55081 | 3q13.12 | Golgi, cilium IFT particles | DNA binding, protein binding | Ciliogenesis, proapoptosis, transcription |
| IRF2BP2 | 359948 | 1q42.3 | Nucleus | Corepressor of IRF-2BP2 | Transcription regulation DNA-dependent |
| PSMC1 | 5700 | 14q32.11 | Cytosol, nucleus, proteasome complex | ATP binding ATPase activity, nucleotide-protein binding | Regulation of ubiquitin-protein ligase activity |
| Gene product . | Gene ID . | Gene chromosomal locus . | Cellular localization . | Molecular function . | Cellular process . |
|---|---|---|---|---|---|
| OFD1 | 8481 | Xp22.2-p22.3 | Basal body/centrosome, cytosol | Unknown | Ciliogenesis |
| ZNF292 | 23036 | 6q15 | Nucleus | DNA binding | Transcription regulation DNA-dependent |
| AKAP11 | 11215 | 13q14.11 | Centrosome, cytosol | PKA binding, PP1-binding | Protein-kinase cascade |
| GPATCH4 | 54865 | 1q22 | Intracellular | Nucleic acid binding | Unknown |
| SON | 6651 | 21q22.1-22.2; 21q22.11 | Intracellular, nucleus | Nucleic acid binding, protein binding | Antiapoptosis |
| FAM50A | 9130 | Xq28 | Nucleus | Unknown | Spermatogenesis |
| SSSCA1 | 10534 | 11q13.1 | Unknown | Protein binding | Cell cycle, cell division, mitosis |
| IFT57/HIPPI | 55081 | 3q13.12 | Golgi, cilium IFT particles | DNA binding, protein binding | Ciliogenesis, proapoptosis, transcription |
| IRF2BP2 | 359948 | 1q42.3 | Nucleus | Corepressor of IRF-2BP2 | Transcription regulation DNA-dependent |
| PSMC1 | 5700 | 14q32.11 | Cytosol, nucleus, proteasome complex | ATP binding ATPase activity, nucleotide-protein binding | Regulation of ubiquitin-protein ligase activity |