Table 4

Multivariate analysis of prognostic variables, serum M-spike response, and PCLI response

Prognostic variableProportional hazard ratio95% CIP
Initial PCLI ≥ 3% 2.71 1.52-4.62 .001* 
Serum M-spike response < 50% 1.47 1.01-2.16 .047* 
PCLI response < 60% 1.70 1.14-2.03 .009* 
β2M > 3.5 mg/dL 1.33 0.87-2.03 .19 
Creatinine > 1.4 1.20 0.76-1.88 .43 
Prognostic variableProportional hazard ratio95% CIP
Initial PCLI ≥ 3% 2.71 1.52-4.62 .001* 
Serum M-spike response < 50% 1.47 1.01-2.16 .047* 
PCLI response < 60% 1.70 1.14-2.03 .009* 
β2M > 3.5 mg/dL 1.33 0.87-2.03 .19 
Creatinine > 1.4 1.20 0.76-1.88 .43 

β2M indicates β2-microglobulin; CI, confidence interval; and PCLI, plasma cell labeling index.

*

Statistically significant.

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