Table 2 Characteristics of complement,... | American Society of Hematology

Table 2

Characteristics of complement, C1 inhibitor levels, and cryoglobulinemia

Patient no.	CH50	C3	C4	Cryoglobulin	C1inh
1	0%	Low	< 15%	Negative	< 30%
2	66%	Normal (0.87 mg/L)	< 25%	Negative	NA
3	75%	Normal (1.3 mg/L)	< 25%	Negative	Normal
4	Low*	Normal	40%	NA	NA
5	Low*	Low*	Low*	Negative	NA
6	Very low*	Normal	Very low*	NA	NA
7	NA	Normal	< 25%	NA	NA
8	NA	Lower limit of normal (0.63 mg/L)	< 40%	Negative	NA
9	NA	NA	NA	NA	NA
10	< 10%	< 50%	< 5%	NA	Low (0.19 g/L)
11	Normal	Normal	< 25%	NA	Normal
12	Low*	Normal	Very low*	NA	NA
13	25%	Normal (1.04 mg/L)	< 25%	Positive (type 1)	Normal
14	< 25%	75%	< 25%	Negative	< 30%
15	Normal (83%)	Normal (0.9 mg/L)	Normal	Positive (type 3)	NA
16	Normal	Normal	Low	Negative	NA
17	Low*	Normal (1.02 mg/L)	< 10%	Negative	Normal
18	Normal	Normal	< 10%	NA	Normal
19	< 25%	Normal	< 10%	Negative	Normal
20	15%	Normal	< 25%	Negative	NA
21	NA	NA	NA	NA	NA
22	< 25%	83%	< 25%	Negative	0%
23†	< 25%	Normal	< 25%	Negative	NA
24	< 25%	45%	< 25%	Negative	NA

Patient no.	CH50	C3	C4	Cryoglobulin	C1inh
1	0%	Low	< 15%	Negative	< 30%
2	66%	Normal (0.87 mg/L)	< 25%	Negative	NA
3	75%	Normal (1.3 mg/L)	< 25%	Negative	Normal
4	Low*	Normal	40%	NA	NA
5	Low*	Low*	Low*	Negative	NA
6	Very low*	Normal	Very low*	NA	NA
7	NA	Normal	< 25%	NA	NA
8	NA	Lower limit of normal (0.63 mg/L)	< 40%	Negative	NA
9	NA	NA	NA	NA	NA
10	< 10%	< 50%	< 5%	NA	Low (0.19 g/L)
11	Normal	Normal	< 25%	NA	Normal
12	Low*	Normal	Very low*	NA	NA
13	25%	Normal (1.04 mg/L)	< 25%	Positive (type 1)	Normal
14	< 25%	75%	< 25%	Negative	< 30%
15	Normal (83%)	Normal (0.9 mg/L)	Normal	Positive (type 3)	NA
16	Normal	Normal	Low	Negative	NA
17	Low*	Normal (1.02 mg/L)	< 10%	Negative	Normal
18	Normal	Normal	< 10%	NA	Normal
19	< 25%	Normal	< 10%	Negative	Normal
20	15%	Normal	< 25%	Negative	NA
21	NA	NA	NA	NA	NA
22	< 25%	83%	< 25%	Negative	0%
23†	< 25%	Normal	< 25%	Negative	NA
24	< 25%	45%	< 25%	Negative	NA

NA indicates not applicable; very low, < 25% of the normal range; and deficiency, < 30% of the normal range.

Corresponding value not available.

Normalization of complement levels while chemotherapy induced complete remission. (Only 1 case with available complement values on chemotherapy.)