Table 5

Cox regression models on relapse-free and overall survival

CN-AMLAll patients
Relapse-free survival (HR, 95% CI)   
    Insertion site in the beta1-sheet 2.05 (1.37-3.06) 1.86 (1.29-2.67) 
Overall survival   
    Insertion site in the beta1-sheet 1.68 (1.17-2.42) 1.59 (1.13-2.24) 
    Logarithm of WBC 1.65 (1.17-2.31) 1.50 (1.10-2.04) 
    CEBPAmut 0.26 (0.10-0.72) 0.31 (0.12-0.83) 
    Age (difference of 10 y) 1.21 (1.00-1.46) 1.22 (1.03-1.44) 
CN-AMLAll patients
Relapse-free survival (HR, 95% CI)   
    Insertion site in the beta1-sheet 2.05 (1.37-3.06) 1.86 (1.29-2.67) 
Overall survival   
    Insertion site in the beta1-sheet 1.68 (1.17-2.42) 1.59 (1.13-2.24) 
    Logarithm of WBC 1.65 (1.17-2.31) 1.50 (1.10-2.04) 
    CEBPAmut 0.26 (0.10-0.72) 0.31 (0.12-0.83) 
    Age (difference of 10 y) 1.21 (1.00-1.46) 1.22 (1.03-1.44) 

CN-AML, cytogenetically normal AML; HR, hazard ratio; CI, confidence interval; WBC, white blood cell count; and CEBPAmut, mutation of the CCAAT/enhancer binding protein alpha.

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