Table 1 Novel TET2 somatic missense... | American Society of Hematology

Table 1

Novel TET2 somatic missense mutations and unannotated SNPs in 4q24

Alteration	Nucleotide change	Genomic coordinate	Amino acid change
Somatic mutation	434 G→A	106374983	S145N
Somatic mutation	935 A→G	106375484	N312S
Somatic mutation	1379 C→T	106375928	S460F
Somatic mutation	1997 A→G	106376546	D666G
Somatic mutation	2821 C→T	106377370	P941S
Somatic mutation	3403 G→A	106377953	C1135Y
Somatic mutation	3575 T→G	106383519	C1194W
Somatic mutation	3609 A→T	106384192	S1204C
Somatic mutation	3639 C→T	106384222	R1214W
Somatic mutation	3724 A→T	106384307	D1242V*
Somatic mutation	3733 A→C	106384316	Y1245S
Somatic mutation	3780 C→T	106384363	R1261C
Somatic mutation	3781 G→A	106384364	R1261H*
Somatic mutation	3862 G→T	106400285	G1289V
Somatic mutation	4074 C→T	106410247	R1358C*
Somatic mutation	4080 G→C	106410253	G1360R
Somatic mutation	4248 G→T	106413237	V1417F
Somatic mutation	5151 G→T	106416269	V1718L*
Somatic mutation	5268 C→G	106416386	H1757D
Somatic mutation	5283 A→T	106416401	Q1828L
Somatic mutation	5430 T→C	106416548	C1811R
Somatic mutation	5617 T→C	106416735	I1873T*
Somatic mutation	5641 A→G	106416759	H1881R*
Somatic mutation	5698 T→C	106416816	V1900A
Somatic mutation	5754 C→T	106416873	A1919V
Somatic mutation	5776 G→A	106416894	R1926H
Somatic mutation	5780 G→A	106416898	R1927K
Somatic mutation	5820 C→T	106416938	P1941S
Somatic mutation	5896 G→A	106417014	R1966H
Somatic mutation	5920 C→T	106417038	R1974M
Somatic mutation	5998 G→A	106417116	R2000K
SNP	100 C→T	106374649	L34F
SNP	520 C→A	106375069	P174H
SNP	2599 T→C	106377148	Y867H
SNP	3418 A→T	106377767	E1073V
SNP	3451 A→C	106377800	Q1084P
SNP	5166 C→T	106416284	P1723S

Alteration	Nucleotide change	Genomic coordinate	Amino acid change
Somatic mutation	434 G→A	106374983	S145N
Somatic mutation	935 A→G	106375484	N312S
Somatic mutation	1379 C→T	106375928	S460F
Somatic mutation	1997 A→G	106376546	D666G
Somatic mutation	2821 C→T	106377370	P941S
Somatic mutation	3403 G→A	106377953	C1135Y
Somatic mutation	3575 T→G	106383519	C1194W
Somatic mutation	3609 A→T	106384192	S1204C
Somatic mutation	3639 C→T	106384222	R1214W
Somatic mutation	3724 A→T	106384307	D1242V*
Somatic mutation	3733 A→C	106384316	Y1245S
Somatic mutation	3780 C→T	106384363	R1261C
Somatic mutation	3781 G→A	106384364	R1261H*
Somatic mutation	3862 G→T	106400285	G1289V
Somatic mutation	4074 C→T	106410247	R1358C*
Somatic mutation	4080 G→C	106410253	G1360R
Somatic mutation	4248 G→T	106413237	V1417F
Somatic mutation	5151 G→T	106416269	V1718L*
Somatic mutation	5268 C→G	106416386	H1757D
Somatic mutation	5283 A→T	106416401	Q1828L
Somatic mutation	5430 T→C	106416548	C1811R
Somatic mutation	5617 T→C	106416735	I1873T*
Somatic mutation	5641 A→G	106416759	H1881R*
Somatic mutation	5698 T→C	106416816	V1900A
Somatic mutation	5754 C→T	106416873	A1919V
Somatic mutation	5776 G→A	106416894	R1926H
Somatic mutation	5780 G→A	106416898	R1927K
Somatic mutation	5820 C→T	106416938	P1941S
Somatic mutation	5896 G→A	106417014	R1966H
Somatic mutation	5920 C→T	106417038	R1974M
Somatic mutation	5998 G→A	106417116	R2000K
SNP	100 C→T	106374649	L34F
SNP	520 C→A	106375069	P174H
SNP	2599 T→C	106377148	Y867H
SNP	3418 A→T	106377767	E1073V
SNP	3451 A→C	106377800	Q1084P
SNP	5166 C→T	106416284	P1723S

Novel unannotated SNPs in 4q24. SNPs were defined as missense mutations that were seen in more than one tumor and paired buccal sample.

Somatic missense mutations that occurred in more than 2 samples.