CLL-attributable mortality for patients diagnosed in the calendar periods 1980-1994 and 1995-2004
| . | Period 1980-1994 . | Period 1995-2004 . | Incidence rate ratio (95% CI) . | P . | ||
|---|---|---|---|---|---|---|
| No. of patients . | Deaths per 1000 patient-years . | No. of patients . | Deaths per 1000 patient-years . | |||
| At 5 years from diagnosis | ||||||
| All patients | 448 | 52 | 358 | 24 | 0.46 (0.28-0.78) | .004 |
| Binet stage A and age younger than 70 y | 167 | 13 | 178 | 14 | 1.08 (0.35-3.31) | .882 |
| Binet stage A and age 70 y and older | 142 | 35 | 108 | 14 | 0.40 (0.06-2.82) | .357 |
| Binet stageB/C and age younger than 70 y | 83 | 143 | 48 | 29 | 0.40 (0.08-0.52) | .001 |
| Binet stage B/C and age 70 y and older | 52 | 135 | 21 | 210 | 1.55 (0.68-3.52) | .292 |
| At 10 years from diagnosis | ||||||
| All patients | 448 | 62 | 358 | 41 | 0.65 (0.48-0.89) | .007 |
| Binet stage A and age younger than 70 y | 167 | 29 | 178 | 27 | 0.92 (0.54-1.55) | .755 |
| Binet stage A and age 70 y and older | 142 | 52 | 108 | 45 | 0.86 (0.43-1.73) | .679 |
| Binet stage B/C and age younger than 70 y | 83 | 144 | 48 | 48 | 0.33 (0.18-0.60) | < .001 |
| Binet stage B/C and age 70 y and older | 52 | 164 | 21 | 197 | 1.20 (0.58-2.50) | .622 |
| . | Period 1980-1994 . | Period 1995-2004 . | Incidence rate ratio (95% CI) . | P . | ||
|---|---|---|---|---|---|---|
| No. of patients . | Deaths per 1000 patient-years . | No. of patients . | Deaths per 1000 patient-years . | |||
| At 5 years from diagnosis | ||||||
| All patients | 448 | 52 | 358 | 24 | 0.46 (0.28-0.78) | .004 |
| Binet stage A and age younger than 70 y | 167 | 13 | 178 | 14 | 1.08 (0.35-3.31) | .882 |
| Binet stage A and age 70 y and older | 142 | 35 | 108 | 14 | 0.40 (0.06-2.82) | .357 |
| Binet stageB/C and age younger than 70 y | 83 | 143 | 48 | 29 | 0.40 (0.08-0.52) | .001 |
| Binet stage B/C and age 70 y and older | 52 | 135 | 21 | 210 | 1.55 (0.68-3.52) | .292 |
| At 10 years from diagnosis | ||||||
| All patients | 448 | 62 | 358 | 41 | 0.65 (0.48-0.89) | .007 |
| Binet stage A and age younger than 70 y | 167 | 29 | 178 | 27 | 0.92 (0.54-1.55) | .755 |
| Binet stage A and age 70 y and older | 142 | 52 | 108 | 45 | 0.86 (0.43-1.73) | .679 |
| Binet stage B/C and age younger than 70 y | 83 | 144 | 48 | 48 | 0.33 (0.18-0.60) | < .001 |
| Binet stage B/C and age 70 y and older | 52 | 164 | 21 | 197 | 1.20 (0.58-2.50) | .622 |