Characteristics of men and women with a first episode of venous thrombosis
| . | Women, n = 523 . | Men, n = 293 . | P . |
|---|---|---|---|
| First venous thrombosis | |||
| Mean age at onset, (SD), y | 34 (15) | 44 (15) | < .001 |
| Unprovoked, no. (%) | 133 (25) | 217 (74) | < .001 |
| Condition that provoked thrombosis, no. (%) | |||
| Oral contraceptives, no. (%) | 114 (22) | ||
| Pregnancy/puerperium, no. (%) | 121 (23) | ||
| Surgery, trauma, immobilization, no. (%) | 148 (28) | 74 (25) | .39 |
| Malignancy, no. (%) | 7 (1) | 2 (1) | .50 |
| Prevalence thrombophilic defects* | |||
| Antithrombin deficiency, less than 70 IU/dL, no. (%) | 22 (4) | 11 (4) | .89 |
| Protein C deficiency, less than 65 IU/dL, no. (%) | 49 (11) | 38 (15) | .14 |
| Protein S deficiency, less than 65 IU/dL, no. (%) | 58 (13) | 34 (13) | .85 |
| FV Leiden, no. (%) | 249 (48) | 127 (43) | .26 |
| FVIII more than 150 IU/dL, no. (%) | 281 (61) | 166 (64) | .39 |
| Prothrombin 20210G>A, no. (%) | 88 (17) | 48 (17) | .999 |
| . | Women, n = 523 . | Men, n = 293 . | P . |
|---|---|---|---|
| First venous thrombosis | |||
| Mean age at onset, (SD), y | 34 (15) | 44 (15) | < .001 |
| Unprovoked, no. (%) | 133 (25) | 217 (74) | < .001 |
| Condition that provoked thrombosis, no. (%) | |||
| Oral contraceptives, no. (%) | 114 (22) | ||
| Pregnancy/puerperium, no. (%) | 121 (23) | ||
| Surgery, trauma, immobilization, no. (%) | 148 (28) | 74 (25) | .39 |
| Malignancy, no. (%) | 7 (1) | 2 (1) | .50 |
| Prevalence thrombophilic defects* | |||
| Antithrombin deficiency, less than 70 IU/dL, no. (%) | 22 (4) | 11 (4) | .89 |
| Protein C deficiency, less than 65 IU/dL, no. (%) | 49 (11) | 38 (15) | .14 |
| Protein S deficiency, less than 65 IU/dL, no. (%) | 58 (13) | 34 (13) | .85 |
| FV Leiden, no. (%) | 249 (48) | 127 (43) | .26 |
| FVIII more than 150 IU/dL, no. (%) | 281 (61) | 166 (64) | .39 |
| Prothrombin 20210G>A, no. (%) | 88 (17) | 48 (17) | .999 |
Numbers of women/men tested for antithrombin, protein C, protein S, factor V Leiden, elevated FVIII, and prothrombin 20210G>A were 513/288, 452/254, 461/254, 517/290, 462/258, and 506/281, respectively.