Summary information of platelet transfusions per treatment group
| Characteristic . | Standard-dose platelet arm, n = 61 . | Low-dose platelet arm, n = 58 . | Mean difference, low dose minus standard dose (95% CI) . | P . |
|---|---|---|---|---|
| Mean (SD) duration of thrombocytopenia, d | 14.0 (9.1) | 15.8 (9.3) | 1.8 (−1.5-5.2) | .281 |
| Platelet transfusion episodes | ||||
| Prophylactic and therapeutic | ||||
| Total no. | 325 | 553 | ||
| Mean (SD) | 5.3 (3.2) | 9.5 (7.8) | 4.2 (2.0-6.4) | .001 |
| Prophylactic only | ||||
| Total no. | 274 | 447 | ||
| Mean (SD) | 4.5 (2.6) | 7.7 (7.1) | 3.2 (1.2-5.2) | .002 |
| Mean no. of platelet transfusions per thrombocytopenic day (SD) | ||||
| Prophylactic and therapeutic | 0.5 (0.3) | 0.6 (0.3) | 0.1 (0.1-0.3) | < .002 |
| Prophylactic only | 0.4 (0.2) | 0.5 (0.3) | 0.1 (0.01-0.2) | .039 |
| Donor exposures | ||||
| All transfusions, prophylactic and therapeutic | ||||
| Total no. | 1354 | 1524 | ||
| Mean (SD) | 22.2 (15.6) | 26.3 (28.2) | 4.1 (−4.3-12.4) | .335 |
| Prophylactic platelet transfusions only | ||||
| Total no. | 1203 | 1254 | ||
| Mean (SD) | 20.1 (15.0) | 22.8 (25.5) | 2.8 (−5.1-10.6) | .487 |
| Mean (SD) interval between platelet transfusions, d | 2.8 (1.8) | 1.8 (1.1) | −1.0 (−1.2, −0.7) | < .001 |
| Characteristic . | Standard-dose platelet arm, n = 61 . | Low-dose platelet arm, n = 58 . | Mean difference, low dose minus standard dose (95% CI) . | P . |
|---|---|---|---|---|
| Mean (SD) duration of thrombocytopenia, d | 14.0 (9.1) | 15.8 (9.3) | 1.8 (−1.5-5.2) | .281 |
| Platelet transfusion episodes | ||||
| Prophylactic and therapeutic | ||||
| Total no. | 325 | 553 | ||
| Mean (SD) | 5.3 (3.2) | 9.5 (7.8) | 4.2 (2.0-6.4) | .001 |
| Prophylactic only | ||||
| Total no. | 274 | 447 | ||
| Mean (SD) | 4.5 (2.6) | 7.7 (7.1) | 3.2 (1.2-5.2) | .002 |
| Mean no. of platelet transfusions per thrombocytopenic day (SD) | ||||
| Prophylactic and therapeutic | 0.5 (0.3) | 0.6 (0.3) | 0.1 (0.1-0.3) | < .002 |
| Prophylactic only | 0.4 (0.2) | 0.5 (0.3) | 0.1 (0.01-0.2) | .039 |
| Donor exposures | ||||
| All transfusions, prophylactic and therapeutic | ||||
| Total no. | 1354 | 1524 | ||
| Mean (SD) | 22.2 (15.6) | 26.3 (28.2) | 4.1 (−4.3-12.4) | .335 |
| Prophylactic platelet transfusions only | ||||
| Total no. | 1203 | 1254 | ||
| Mean (SD) | 20.1 (15.0) | 22.8 (25.5) | 2.8 (−5.1-10.6) | .487 |
| Mean (SD) interval between platelet transfusions, d | 2.8 (1.8) | 1.8 (1.1) | −1.0 (−1.2, −0.7) | < .001 |