Table 4

Frequency of bleeding (WHO grades 1-4) in the 2 treatment groups

Type of bleedingTreatment group
Standard dose, n = 61Low dose, n = 58
No. of patients with bleeding (%)   
    Grade 1 48 (78.7) 53 (91.4) 
    Grade 2 28 (45.9) 28 (48.3) 
    Grade 3 6 (9.8) 5 (8.6) 
    Grade 4 0 (0.0) 3 (5.2) 
    Grade 2 or higher 30 (49.2) 30 (51.7) 
Percentage of days with bleeding (proportion)*   
    Grade 2 or higher 8.5 (73/854) 12.1 (111/918) 
    Grade 4 0.0 (0/854) 0.5 (5/918) 
Type of bleedingTreatment group
Standard dose, n = 61Low dose, n = 58
No. of patients with bleeding (%)   
    Grade 1 48 (78.7) 53 (91.4) 
    Grade 2 28 (45.9) 28 (48.3) 
    Grade 3 6 (9.8) 5 (8.6) 
    Grade 4 0 (0.0) 3 (5.2) 
    Grade 2 or higher 30 (49.2) 30 (51.7) 
Percentage of days with bleeding (proportion)*   
    Grade 2 or higher 8.5 (73/854) 12.1 (111/918) 
    Grade 4 0.0 (0/854) 0.5 (5/918) 
*

Expressed as a percentage of thrombocytopenic days.

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