Table 2

Cutaneous lymphomas diagnosed during 2001-2005 in the 16 SEER program registries by histologic type and race/ethnicity

TotalRate*Non-Hispanic white
Black
Hispanic white
Asian/PacificIslander
B:NHW
HW:NHW
A/PI:NHW
CasesRateCasesRateCasesRateCasesRateIRRPIRRPIRRP
Total 3874§ 10.7 2919 11.5 400 11.5 328 7.9 227 7.1 0.99 .507 0.69 < .001 0.61 < .0001 
Mature T-cell and NK-cell neoplasms (CTCLs) 2769 7.7 2032 8.1 349 10.0 219 5.1 169 5.1 1.24 .001 0.64 < .001 0.64 < .0001 
    Mycosis fungoides (MF) 1487 4.1 1033 4.1 212 5.9 132 2.9 110 3.3 1.44 < .001 0.71 .001 0.80 .0251 
    Sézary syndrome (SS) 33 0.1 28 0.1 1 ∼‖ 4 ∼ 0 ∼ ∼ ∼ ∼ ∼ ∼ ∼ 
    CD30+ T-cell lymphoproliferative disorders of the skin (CD30+ LPD) 396 1.1 315 1.3 31 0.9 29 0.7 21 0.7 0.71 .076 0.57 .004 0.52 .002 
    Subcutaneous panniculitis-like T-cell lymphoma (SCPTL) 23 0.1 11 0.0 6 ∼ 0 ∼ 6 ∼ ∼ ∼ ∼ ∼ ∼ ∼ 
    Primary cutaneous peripheral T-cell lymphoma (pcPTL) 809 2.2 634 2.5 96 2.8 50 1.3 29 1.0 1.14 .285 0.52 < .001 0.38 < .0001 
    Other‡ 21 0.1 11 0.0 3 ∼ 5 ∼ 2 ∼ ∼ ∼ ∼ ∼ ∼ ∼ 
Mature B-cell neoplasms (CBCLs) 1105 3.1 887 3.5 51 1.5 109 2.8 58 1.9 0.43 < .001 0.80 .038 0.55 < .0001 
    Cutaneous marginal zone B-cell lymphoma (pcMZL) 274 0.8 219 0.9 12 0.3 31 0.7 12 0.4 0.37 .001 0.83 .381 0.42 .0016 
    Cutaneous follicle center lymphoma (pcFCL) 331 0.9 281 1.1 11 0.4 29 0.7 10 0.3 0.33 < .001 0.62 .015 0.29 < .0001 
    Cutaneous diffuse large B-cell lymphoma (pcDLBCL) 443 1.2 347 1.3 23 0.7 42 1.2 31 1.1 0.50 .001 0.89 .525 0.80 .2579 
        pcDLBCL-leg 101 0.3 70 0.3 4 ∼ 12 0.4 15 0.5 0.49 .186 1.62 .194 2.10 .0263 
        pcDLBCL-other 342 1.0 277 1.1 19 0.5 30 0.8 16 0.5 0.51 .003 0.71 .103 0.49 .0029 
    Extracutaneous lymphomas involving the skin§ 57 0.2 40 0.2 5 ∼ 7 ∼ 5 ∼ ∼ ∼ ∼ ∼ ∼ ∼ 
TotalRate*Non-Hispanic white
Black
Hispanic white
Asian/PacificIslander
B:NHW
HW:NHW
A/PI:NHW
CasesRateCasesRateCasesRateCasesRateIRRPIRRPIRRP
Total 3874§ 10.7 2919 11.5 400 11.5 328 7.9 227 7.1 0.99 .507 0.69 < .001 0.61 < .0001 
Mature T-cell and NK-cell neoplasms (CTCLs) 2769 7.7 2032 8.1 349 10.0 219 5.1 169 5.1 1.24 .001 0.64 < .001 0.64 < .0001 
    Mycosis fungoides (MF) 1487 4.1 1033 4.1 212 5.9 132 2.9 110 3.3 1.44 < .001 0.71 .001 0.80 .0251 
    Sézary syndrome (SS) 33 0.1 28 0.1 1 ∼‖ 4 ∼ 0 ∼ ∼ ∼ ∼ ∼ ∼ ∼ 
    CD30+ T-cell lymphoproliferative disorders of the skin (CD30+ LPD) 396 1.1 315 1.3 31 0.9 29 0.7 21 0.7 0.71 .076 0.57 .004 0.52 .002 
    Subcutaneous panniculitis-like T-cell lymphoma (SCPTL) 23 0.1 11 0.0 6 ∼ 0 ∼ 6 ∼ ∼ ∼ ∼ ∼ ∼ ∼ 
    Primary cutaneous peripheral T-cell lymphoma (pcPTL) 809 2.2 634 2.5 96 2.8 50 1.3 29 1.0 1.14 .285 0.52 < .001 0.38 < .0001 
    Other‡ 21 0.1 11 0.0 3 ∼ 5 ∼ 2 ∼ ∼ ∼ ∼ ∼ ∼ ∼ 
Mature B-cell neoplasms (CBCLs) 1105 3.1 887 3.5 51 1.5 109 2.8 58 1.9 0.43 < .001 0.80 .038 0.55 < .0001 
    Cutaneous marginal zone B-cell lymphoma (pcMZL) 274 0.8 219 0.9 12 0.3 31 0.7 12 0.4 0.37 .001 0.83 .381 0.42 .0016 
    Cutaneous follicle center lymphoma (pcFCL) 331 0.9 281 1.1 11 0.4 29 0.7 10 0.3 0.33 < .001 0.62 .015 0.29 < .0001 
    Cutaneous diffuse large B-cell lymphoma (pcDLBCL) 443 1.2 347 1.3 23 0.7 42 1.2 31 1.1 0.50 .001 0.89 .525 0.80 .2579 
        pcDLBCL-leg 101 0.3 70 0.3 4 ∼ 12 0.4 15 0.5 0.49 .186 1.62 .194 2.10 .0263 
        pcDLBCL-other 342 1.0 277 1.1 19 0.5 30 0.8 16 0.5 0.51 .003 0.71 .103 0.49 .0029 
    Extracutaneous lymphomas involving the skin§ 57 0.2 40 0.2 5 ∼ 7 ∼ 5 ∼ ∼ ∼ ∼ ∼ ∼ ∼ 

IRR indicates incidence rate ratio; and pc, primary cutaneous.

*

Rates are per 1 000 000 and age-adjusted to the 2000 US standard population (19 age groups; Census P25-1130).

‡

Other includes extranodal NK/T-cell lymphoma, adult T-cell leukemia/lymphoma, and angioimmunoblastic T-cell lymphoma.

§

This group includes small lymphocytic lymphoma, lymphoplasmacytic lymphoma, mantle cell lymphoma, and Burkitt lymphoma. Immature hematologic neoplasms were excluded (n=10) due to small numbers.

‖

Statistic not shown, based on fewer than 10 cases.

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