Table 2 Extent of uPA colocalization... | American Society of Hematology

Table 2

Extent of uPA colocalization with other α-granule proteins in QPD platelets

Protein colocalized with uPA	Mean ± SD (range)
Protein colocalized with uPA	Pearson correlation coefficient, r_p	Manders overlap coefficient, r
Plasminogen	0.98 ± 0.01 (0.95-1.00)*	0.99 ± 0.01 (0.97-1.00)*
TSP-1	0.92 ± 0.04 (0.81-0.99)	0.96 ± 0.02 (0.93-0.99)
Osteonectin	0.83 ± 0.09 (0.64-0.96)†	0.88 ± 0.07 (0.76-0.97)†
Fibrinogen	0.81 ± 0.08 (0.52-0.88)†	0.91 ± 0.03 (0.80-0.94)†
VEGF	0.69 ± 0.14 (0.25-0.89)†	0.85 ± 0.07 (0.61-0.96)†
VWF	0.68 ± 0.14 (0.42-0.90)†	0.86 ± 0.06 (0.70-0.96)†
Factor V	0.66 ± 0.14 (0.32-0.89)†	0.85 ± 0.07 (0.68-0.96)†

Protein colocalized with uPA	Mean ± SD (range)
Protein colocalized with uPA	Pearson correlation coefficient, r_p	Manders overlap coefficient, r
Plasminogen	0.98 ± 0.01 (0.95-1.00)*	0.99 ± 0.01 (0.97-1.00)*
TSP-1	0.92 ± 0.04 (0.81-0.99)	0.96 ± 0.02 (0.93-0.99)
Osteonectin	0.83 ± 0.09 (0.64-0.96)†	0.88 ± 0.07 (0.76-0.97)†
Fibrinogen	0.81 ± 0.08 (0.52-0.88)†	0.91 ± 0.03 (0.80-0.94)†
VEGF	0.69 ± 0.14 (0.25-0.89)†	0.85 ± 0.07 (0.61-0.96)†
VWF	0.68 ± 0.14 (0.42-0.90)†	0.86 ± 0.06 (0.70-0.96)†
Factor V	0.66 ± 0.14 (0.32-0.89)†	0.85 ± 0.07 (0.68-0.96)†

Greater colocalization with uPA than other evaluated proteins; P < .001.

Less colocalization with uPA than plasminogen and TSP-1; P < .001.