Platelests (100 × 10³/μL) were activated with TRAP-6 for 2 minutes and then incubated for 1 minute at 37°C alone or in the presence of an equal volume of neutrophils, at a neutrophil:platelet ratio of 1:20, 1:10, or 1:5. Neutrophils at the 1:5 ratio were either untreated or pretreated with cytochalasin D to prevent actin-based cytoskeleton assembly. After addition of normal human plasma and of a 25 mM CaCl2 solution, the coagulation (recalcification) time was recorded and expressed as seconds (mean ± SEM of 5 different experiment performed in duplicate). The platelet phagocytosis by neutrophils was confirmed in parallel by flow cytometry. *P < .05 with respect to samples with activated platelets alone (by paired t test).