Table 1 FXI inhibition by aXIMab... | American Society of Hematology

Table 1

FXI inhibition by aXIMab prevents occlusion of 2-mm id vascular grafts in baboons

	Number occluded	Embolic events per experiment*	Fibrin deposition, mg
Control	8/9	ND	0.30 ± 0.04
ASA	4/6	1.5 ± 0.6	0.23 ± 0.04
aXIMab	0/5	6.6 ± 0.9	0.18 ± 0.02†

	Number occluded	Embolic events per experiment*	Fibrin deposition, mg
Control	8/9	ND	0.30 ± 0.04
ASA	4/6	1.5 ± 0.6	0.23 ± 0.04
aXIMab	0/5	6.6 ± 0.9	0.18 ± 0.02†

Data shown are absolute values or means plus or minus SEM when applicable.

ND indicates none detected.

Embolic events were defined as an abrupt decrease of at least 10⁶ platelets in the graft between 2 subsequent radioimaging frames.

P < .01 compared with control using the 2-tailed Student t test.