Table 1

Patient characteristics

ParameterSubgroup of patients
Donor (n = 96)No donor (n = 161)
Median age, y (range) 31 (16-55) 26 (15-54) 
Sex 
    Male 58 (60) 96 (60) 
    Female 38 (40) 65 (40) 
Immunophenotype (No.) 
    Precursor B cell 65 (68) 121 (75) 
    Precursor T cell 28 (29) 38 (24) 
    Not specified 
WBC, × 109/L (No. [%]) 
    ≤ 30 64 (67) 118 (73) 
    30-100 18 (19) 26 (16) 
    > 100 14 (15) 17 (11) 
Cytogenetics successful (No. [%]) 79 (82) 130 (81) 
Cytogenetic poor-risk features* 
    t(9;22) 17 (22) 21 (16) 
    t(4;11) 4 (5) 4 (3) 
    t(1;19) 1 (1) 3 (2) 
Cycles to CR (No. [%]) 
    1 87 (91) 148 (92) 
    2-3 9 (9) 13 (8) 
Prognostic risk category (No. [%]) 
    Standard 50 (52) 88 (55) 
    Poor 46 (48) 73 (45) 
Time from diagnosis until SCT, mo 
    Median (range) 5.2 (2.8-10.8) 5.4 (3.2-10.2) 
Time from CR1 until SCT, mo 
    Median (range) 3.8 (0.5-9.2) 3.9 (0.4-8.9) 
ParameterSubgroup of patients
Donor (n = 96)No donor (n = 161)
Median age, y (range) 31 (16-55) 26 (15-54) 
Sex 
    Male 58 (60) 96 (60) 
    Female 38 (40) 65 (40) 
Immunophenotype (No.) 
    Precursor B cell 65 (68) 121 (75) 
    Precursor T cell 28 (29) 38 (24) 
    Not specified 
WBC, × 109/L (No. [%]) 
    ≤ 30 64 (67) 118 (73) 
    30-100 18 (19) 26 (16) 
    > 100 14 (15) 17 (11) 
Cytogenetics successful (No. [%]) 79 (82) 130 (81) 
Cytogenetic poor-risk features* 
    t(9;22) 17 (22) 21 (16) 
    t(4;11) 4 (5) 4 (3) 
    t(1;19) 1 (1) 3 (2) 
Cycles to CR (No. [%]) 
    1 87 (91) 148 (92) 
    2-3 9 (9) 13 (8) 
Prognostic risk category (No. [%]) 
    Standard 50 (52) 88 (55) 
    Poor 46 (48) 73 (45) 
Time from diagnosis until SCT, mo 
    Median (range) 5.2 (2.8-10.8) 5.4 (3.2-10.2) 
Time from CR1 until SCT, mo 
    Median (range) 3.8 (0.5-9.2) 3.9 (0.4-8.9) 

CR indicates complete remission; and WBC, white blood cell count.

*

Restricted to patients with successful cytogenetics.

Based on cytogenetics, WBC count, and early or late attainment of CR (see “Methods”).

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