Characteristics of 1143 relatives of probands with a thrombophilic defect
| Characteristic . | Value (%) . |
|---|---|
| Male | 532 (47) |
| Age at enrollment, y | 45 (17) |
| Free protein S levels, IU/dL | 80 (22) |
| In males | 83 (25) |
| In females | 75 (21) |
| First venous thrombosis | 96 (8) |
| Age at onset, y | 39 (15) |
| Classification | |
| Idiopathic | 34 (35) |
| Provoked | 62 (65) |
| Surgery, trauma, immobilization | 26 |
| Oral contraception/hormonal replacement therapy | 18 |
| Pregnancy, puerperium | 17 |
| Malignancy | 1 |
| Concomitant thrombophilic defects | |
| Antithrombin deficiency | 54 (5) |
| Protein C deficiency | 69 (6) |
| Factor V Leiden | 157 (14) |
| Prothrombin G20210A | 97 (8) |
| Factor VIII > 150 IU/dL | 443 (39) |
| Characteristic . | Value (%) . |
|---|---|
| Male | 532 (47) |
| Age at enrollment, y | 45 (17) |
| Free protein S levels, IU/dL | 80 (22) |
| In males | 83 (25) |
| In females | 75 (21) |
| First venous thrombosis | 96 (8) |
| Age at onset, y | 39 (15) |
| Classification | |
| Idiopathic | 34 (35) |
| Provoked | 62 (65) |
| Surgery, trauma, immobilization | 26 |
| Oral contraception/hormonal replacement therapy | 18 |
| Pregnancy, puerperium | 17 |
| Malignancy | 1 |
| Concomitant thrombophilic defects | |
| Antithrombin deficiency | 54 (5) |
| Protein C deficiency | 69 (6) |
| Factor V Leiden | 157 (14) |
| Prothrombin G20210A | 97 (8) |
| Factor VIII > 150 IU/dL | 443 (39) |
Continuous variables are denoted as mean (SD). Categorical variables are denoted as number (percent).