Predictors of response to eradication therapy
| Study . | No. of bacterial eradication cases . | Characteristics predicting response . | Characteristics not predicting response . |
|---|---|---|---|
| Ando et al (2003)22 | 27 | No prior corticosteroid therapy | Sex, age, ITP duration, baseline platelet count, pretreatment of H pylori antibody levels and PAIgG levels |
| Sato et al (2004)25 | 27 | No concomitant corticosteroid therapy | Sex, age, ITP duration, baseline platelet count, previous splenectomy |
| Ando et al (2004)26 | 15 | Age ≥ 60 y at the time of ITP diagnosis | None |
| Veneri et al (2005)28 | 32 | HLA-DQB1*03 allele | None |
| Inaba et al (2005)29 | 25 | None | Sex, age, ITP duration, baseline platelet count, PAIgG levels, previous drug therapy, previous splenectomy |
| Stasi et al (2005)30 | 52 | Age < 65 y, higher baseline platelet count, shorter ITP duration, no prior therapy for ITP | Sex, PAIgG levels |
| Fujimura et al (2005)39 | 161 | Shorter ITP duration | Sex, age, baseline platelet count, ITP treatment before eradication |
| Suzuki et al (2005)17 | 22 | None | Sex, age, ITP duration, previous corticosteroid therapy |
| Suvajdzić et al (2006)31 | 23 | None | Previous corticosteroid therapy, response to corticosteroids |
| Asahi et al (2006)34 | 26 | None | Antinuclear antibodies |
| Kodama et al (2007)35 | 44 | Shorter ITP duration | Sex, age, baseline platelet count, drug treatment before eradication, splenectomy, serum levels of gastrin, pepsinogen and anti-CagA antibodies |
| Satake et al (2007)37 | 23 | Lower baseline platelet count | Sex, age, ITP treatment before eradication, history of peptic ulcer |
| Emilia et al (2007)38 | 34 | None | Sex, age, ITP duration, baseline platelet count, ITP treatment before eradication |
| Study . | No. of bacterial eradication cases . | Characteristics predicting response . | Characteristics not predicting response . |
|---|---|---|---|
| Ando et al (2003)22 | 27 | No prior corticosteroid therapy | Sex, age, ITP duration, baseline platelet count, pretreatment of H pylori antibody levels and PAIgG levels |
| Sato et al (2004)25 | 27 | No concomitant corticosteroid therapy | Sex, age, ITP duration, baseline platelet count, previous splenectomy |
| Ando et al (2004)26 | 15 | Age ≥ 60 y at the time of ITP diagnosis | None |
| Veneri et al (2005)28 | 32 | HLA-DQB1*03 allele | None |
| Inaba et al (2005)29 | 25 | None | Sex, age, ITP duration, baseline platelet count, PAIgG levels, previous drug therapy, previous splenectomy |
| Stasi et al (2005)30 | 52 | Age < 65 y, higher baseline platelet count, shorter ITP duration, no prior therapy for ITP | Sex, PAIgG levels |
| Fujimura et al (2005)39 | 161 | Shorter ITP duration | Sex, age, baseline platelet count, ITP treatment before eradication |
| Suzuki et al (2005)17 | 22 | None | Sex, age, ITP duration, previous corticosteroid therapy |
| Suvajdzić et al (2006)31 | 23 | None | Previous corticosteroid therapy, response to corticosteroids |
| Asahi et al (2006)34 | 26 | None | Antinuclear antibodies |
| Kodama et al (2007)35 | 44 | Shorter ITP duration | Sex, age, baseline platelet count, drug treatment before eradication, splenectomy, serum levels of gastrin, pepsinogen and anti-CagA antibodies |
| Satake et al (2007)37 | 23 | Lower baseline platelet count | Sex, age, ITP treatment before eradication, history of peptic ulcer |
| Emilia et al (2007)38 | 34 | None | Sex, age, ITP duration, baseline platelet count, ITP treatment before eradication |
PAIgG indicates platelet-associated IgG.