CEBPA mutations and predicted effects
| Pt no. . | BP change . | AA change . | Predicted effect . |
|---|---|---|---|
| 1 | 322-323insT | Y108fsX169 | N-terminal Stop |
| 2 | 317-320dup | D107fsX108 | N-terminal Stop |
| 915-938dup | R306-K313dup | In-frame duplication in bZip | |
| 3 | 312-313insCAGCTTC | G104fsX109 | N-terminal Stop |
| 950-951insTCT | L317-T318insL | In-frame insertion in bZip | |
| 4 | 68del | P23fsX159 | N-terminal Stop |
| 936-938dup | K313dup | In-frame duplication in bZip | |
| 5 | 258-259delinsAT | Q87X | N-terminal Stop |
| 915-938dup | R306-K313dup | In-frame duplication in bZip | |
| 6 | 68-78del | P23fsX103 | N-terminal Stop |
| 893-928dup | K298-E309dup | In-frame duplication in bZip | |
| 7 | 270del | K90fsX159 | N-terminal Stop |
| 976-977insCGCTGGGAA | K326TinsLGK | In-frame insertion in bZip | |
| 8 | 68del | P23fsX159 | N-terminal Stop |
| 921-938dup | V308-K313dup | In-frame duplication in bZip | |
| 9 | 123-124insGC | G54fsX160 | N-terminal Stop |
| 914-916dup | Q105dup | In-frame duplication in bZip | |
| 10 | 68-69insC | P23fsX107 | N-terminal Stop |
| 893-928dup | K298-E309dup | In-frame duplication in bZip | |
| 11 | 258-259delinsAT | Q87X | N-terminal Stop |
| 936-938dup | K313dup | In-frame duplication in bZip | |
| 12 | 59-60dup | S60fsX160 | N-terminal Stop |
| 934-936dup | Q312dup | In-frame duplication in bZip | |
| 13 | 262-263insTTGGCAC | Q88fsX109 | N-terminal Stop |
| 937-942dup | K313-V314dup | In-frame duplication in bZip | |
| 14 | 247-250dup | H84fsX108 | N-terminal Stop |
| 937-939dup | K313dup | In-frame duplication in bZip | |
| 15 | 196del | A66fsX159 | N-terminal Stop |
| 950-951ins24bp | L317-T318ins8aa | In-frame insertion in bZip | |
| 16 | 177-186del | E59fsX156 | N-terminal Stop |
| 932-949del | Q311-E316del | In-frame deletion in bZip | |
| 17 | 68del | P23fsX159 | N-terminal Stop |
| 944-945insGCA | L315-E316insQ | In-frame insertion in bZip | |
| 18 | 201dup | I68fsX107 | N-terminal Stop |
| 937-939dup | K313dup | In-frame duplication in bZip | |
| 19 | 162-172del | G54fsX103 | N-terminal Stop |
| 938-940dup | K313-V314insE | In-frame insertion in bZip | |
| 20 | 246del | F82fsX159 | N-terminal Stop |
| 956-957insCGG | S319-D320insG | In-frame insertion in bZip | |
| 21 | 151del | P51fsX159 | N-terminal Stop |
| 921-926del | N307-V308delinsK | In-frame deletion in bZip | |
| 22 | 147del | P49fsX159 | N-terminal Stop |
| 937-939del | K313del | In-frame deletion in bZip | |
| 23 | 276-292del | K92fsX101 | N-terminal Stop |
| 937-939dup | K313dup | In-frame duplication in bZip | |
| 24 | 258-259delinsAT | Q87X | N-terminal Stop |
| 897-920dup | R300-N307dup | In-frame duplication in bZip | |
| 25 | 177-186del | E49fsX156 | N-terminal Stop |
| 931-933dup | Q311dup | In-frame duplication in bZip | |
| 26 | 246del | F82fsX159 | N-terminal Stop |
| 937-939dup | K313dup | In-frame duplication in bZip | |
| 27 | 247dup | Q83fsX107 | N-terminal Stop |
| 970-975dup | L324-R325dup | In-frame duplication in bZip | |
| 28 | 246-247insGT | Q83fsX160 | N-terminal Stop |
| 1013-1072dup | T337-N356dup | In-frame duplication in bZip | |
| 29 | 247dup | Q83fsX107 | N-terminal Stop |
| 970-975dup | L324-R325dup | In-frame duplication in bZip | |
| 30 | 258-259delinsAT | Q87X | N-terminal Stop |
| 931-933dup | Q311dup | In-frame duplication in bZip | |
| 31 | 319-320insCTTG | A107fsX170 | N-terminal Stop |
| 937-939dup | K313dup | In-frame duplication in bZip | |
| 32 | 281del | A94fsX159 | N-terminal Stop |
| 929-937dup | T310-Q312dup | In-frame duplication in bZip | |
| 33 | |||
| 931-939dup | Q311-K313dup | In-frame duplication in bZip | |
| 34 | |||
| 937-939dup | K313dup | In-frame duplication in bZip | |
| 35 | |||
| 936-938dup | K313dup | In-frame duplication in bZip | |
| 36 | |||
| 915-938dup | R306-K313dup | In-frame duplication in bZip | |
| 37 | |||
| 926-927insTGA | E309DinsE | In-frame insertion in bZip | |
| 38 | |||
| 931-933dup | Q311dup | In-frame duplication in bZip |
| Pt no. . | BP change . | AA change . | Predicted effect . |
|---|---|---|---|
| 1 | 322-323insT | Y108fsX169 | N-terminal Stop |
| 2 | 317-320dup | D107fsX108 | N-terminal Stop |
| 915-938dup | R306-K313dup | In-frame duplication in bZip | |
| 3 | 312-313insCAGCTTC | G104fsX109 | N-terminal Stop |
| 950-951insTCT | L317-T318insL | In-frame insertion in bZip | |
| 4 | 68del | P23fsX159 | N-terminal Stop |
| 936-938dup | K313dup | In-frame duplication in bZip | |
| 5 | 258-259delinsAT | Q87X | N-terminal Stop |
| 915-938dup | R306-K313dup | In-frame duplication in bZip | |
| 6 | 68-78del | P23fsX103 | N-terminal Stop |
| 893-928dup | K298-E309dup | In-frame duplication in bZip | |
| 7 | 270del | K90fsX159 | N-terminal Stop |
| 976-977insCGCTGGGAA | K326TinsLGK | In-frame insertion in bZip | |
| 8 | 68del | P23fsX159 | N-terminal Stop |
| 921-938dup | V308-K313dup | In-frame duplication in bZip | |
| 9 | 123-124insGC | G54fsX160 | N-terminal Stop |
| 914-916dup | Q105dup | In-frame duplication in bZip | |
| 10 | 68-69insC | P23fsX107 | N-terminal Stop |
| 893-928dup | K298-E309dup | In-frame duplication in bZip | |
| 11 | 258-259delinsAT | Q87X | N-terminal Stop |
| 936-938dup | K313dup | In-frame duplication in bZip | |
| 12 | 59-60dup | S60fsX160 | N-terminal Stop |
| 934-936dup | Q312dup | In-frame duplication in bZip | |
| 13 | 262-263insTTGGCAC | Q88fsX109 | N-terminal Stop |
| 937-942dup | K313-V314dup | In-frame duplication in bZip | |
| 14 | 247-250dup | H84fsX108 | N-terminal Stop |
| 937-939dup | K313dup | In-frame duplication in bZip | |
| 15 | 196del | A66fsX159 | N-terminal Stop |
| 950-951ins24bp | L317-T318ins8aa | In-frame insertion in bZip | |
| 16 | 177-186del | E59fsX156 | N-terminal Stop |
| 932-949del | Q311-E316del | In-frame deletion in bZip | |
| 17 | 68del | P23fsX159 | N-terminal Stop |
| 944-945insGCA | L315-E316insQ | In-frame insertion in bZip | |
| 18 | 201dup | I68fsX107 | N-terminal Stop |
| 937-939dup | K313dup | In-frame duplication in bZip | |
| 19 | 162-172del | G54fsX103 | N-terminal Stop |
| 938-940dup | K313-V314insE | In-frame insertion in bZip | |
| 20 | 246del | F82fsX159 | N-terminal Stop |
| 956-957insCGG | S319-D320insG | In-frame insertion in bZip | |
| 21 | 151del | P51fsX159 | N-terminal Stop |
| 921-926del | N307-V308delinsK | In-frame deletion in bZip | |
| 22 | 147del | P49fsX159 | N-terminal Stop |
| 937-939del | K313del | In-frame deletion in bZip | |
| 23 | 276-292del | K92fsX101 | N-terminal Stop |
| 937-939dup | K313dup | In-frame duplication in bZip | |
| 24 | 258-259delinsAT | Q87X | N-terminal Stop |
| 897-920dup | R300-N307dup | In-frame duplication in bZip | |
| 25 | 177-186del | E49fsX156 | N-terminal Stop |
| 931-933dup | Q311dup | In-frame duplication in bZip | |
| 26 | 246del | F82fsX159 | N-terminal Stop |
| 937-939dup | K313dup | In-frame duplication in bZip | |
| 27 | 247dup | Q83fsX107 | N-terminal Stop |
| 970-975dup | L324-R325dup | In-frame duplication in bZip | |
| 28 | 246-247insGT | Q83fsX160 | N-terminal Stop |
| 1013-1072dup | T337-N356dup | In-frame duplication in bZip | |
| 29 | 247dup | Q83fsX107 | N-terminal Stop |
| 970-975dup | L324-R325dup | In-frame duplication in bZip | |
| 30 | 258-259delinsAT | Q87X | N-terminal Stop |
| 931-933dup | Q311dup | In-frame duplication in bZip | |
| 31 | 319-320insCTTG | A107fsX170 | N-terminal Stop |
| 937-939dup | K313dup | In-frame duplication in bZip | |
| 32 | 281del | A94fsX159 | N-terminal Stop |
| 929-937dup | T310-Q312dup | In-frame duplication in bZip | |
| 33 | |||
| 931-939dup | Q311-K313dup | In-frame duplication in bZip | |
| 34 | |||
| 937-939dup | K313dup | In-frame duplication in bZip | |
| 35 | |||
| 936-938dup | K313dup | In-frame duplication in bZip | |
| 36 | |||
| 915-938dup | R306-K313dup | In-frame duplication in bZip | |
| 37 | |||
| 926-927insTGA | E309DinsE | In-frame insertion in bZip | |
| 38 | |||
| 931-933dup | Q311dup | In-frame duplication in bZip |