Outcome by different CD20 expression cut points in precursor B-cell ALL: pre-rituximab era
Age, y . | Parameter (percent at 3 y) . | Hyper-CVAD . | VAD/CVAD . | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
< 10 . | ≥ 10 . | < 20 . | ≥ 20 . | < 30 . | ≥ 30 . | < 10 . | ≥ 10 . | < 20 . | ≥ 20 . | < 30 . | ≥ 30 . | ||
≤ 30 | CRD | 69 | 33* | 68 | 22* | 64 | 20* | 50 | 21 | 65 | 15* | 55 | 27 |
OS | 90 | 45* | 85 | 35* | 82 | 30* | 40 | 40 | 50 | 35 | 44 | 41 | |
31-59 | CRD | 64 | 28* | 56 | 30* | 47 | 35 | 20 | 20 | 18 | 18 | 18 | 18 |
OS | 50 | 27* | 54 | 28* | 35 | 35 | 12 | 25 | 15 | 30 | 14 | 35 | |
≥ 60 | CRD | 42 | 0 | 43 | 0 | 42 | 0 | 54 | 12 | 35 | 16 | 30 | 0 |
OS | 18 | 22 | 20 | 20 | 20 | 22 | 12 | 6 | 8 | 12 | 10 | 0 |
Age, y . | Parameter (percent at 3 y) . | Hyper-CVAD . | VAD/CVAD . | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
< 10 . | ≥ 10 . | < 20 . | ≥ 20 . | < 30 . | ≥ 30 . | < 10 . | ≥ 10 . | < 20 . | ≥ 20 . | < 30 . | ≥ 30 . | ||
≤ 30 | CRD | 69 | 33* | 68 | 22* | 64 | 20* | 50 | 21 | 65 | 15* | 55 | 27 |
OS | 90 | 45* | 85 | 35* | 82 | 30* | 40 | 40 | 50 | 35 | 44 | 41 | |
31-59 | CRD | 64 | 28* | 56 | 30* | 47 | 35 | 20 | 20 | 18 | 18 | 18 | 18 |
OS | 50 | 27* | 54 | 28* | 35 | 35 | 12 | 25 | 15 | 30 | 14 | 35 | |
≥ 60 | CRD | 42 | 0 | 43 | 0 | 42 | 0 | 54 | 12 | 35 | 16 | 30 | 0 |
OS | 18 | 22 | 20 | 20 | 20 | 22 | 12 | 6 | 8 | 12 | 10 | 0 |
ρ <.05 for comparator of above and below specified percent CD20 expression for CRD or OS.