Second cancers and stem cell collection/purging procedures used for patients in the HDT arm (84 patients)
| Purging method . | HSC source . | No. of patients . | Secondary malignancies . | |
|---|---|---|---|---|
| No. and type . | % . | |||
| CD34+ | PBSC | 55 | 1 BC, 1 RC, 1 PC, 1 AML, 1 MDS | 9 |
| BM | 1 | 0 | ||
| BM + purged PBSC | 1 | 0 | ||
| CD34− | PBSC | 4 | 1 MDS | 33* |
| BM | 8 | 2 MDS, 1 BC | ||
| Unpurged | PBSC | 3 | 1 RC | |
| BM | 1 | 0 | ||
| BM + PBSC | 1 | 0 | ||
| No transplant | NA | 9 | 1 LC, 1 MDS | |
| Allo-SCT | Allogeneic PBSC | 1 | 0 | |
| Purging method . | HSC source . | No. of patients . | Secondary malignancies . | |
|---|---|---|---|---|
| No. and type . | % . | |||
| CD34+ | PBSC | 55 | 1 BC, 1 RC, 1 PC, 1 AML, 1 MDS | 9 |
| BM | 1 | 0 | ||
| BM + purged PBSC | 1 | 0 | ||
| CD34− | PBSC | 4 | 1 MDS | 33* |
| BM | 8 | 2 MDS, 1 BC | ||
| Unpurged | PBSC | 3 | 1 RC | |
| BM | 1 | 0 | ||
| BM + PBSC | 1 | 0 | ||
| No transplant | NA | 9 | 1 LC, 1 MDS | |
| Allo-SCT | Allogeneic PBSC | 1 | 0 | |
HSC indicates hematopoietic stem cell; Allo-SCT, allogeneic stem cell transplantation; PBSC, peripheral blood stem cells; BC, breast cancer; RC, renal cancer; PC, prostate cancer; BM, bone marrow; LC, lung cancer; and NA, not applicable.
For CD34+ versus CD34− purging, P = .02.