Table 3

DA-EPOCH-B overall response and by molecular subtype

Treatment groupn (%)Response, n (%)
P*
CompletePartialNone
All patients 44 8 (18) 7 (16) 29 (66)  
DLBCL (de novo) 31 (70) 7 (23) 6 (19) 18 (58) .63 
Molecular subtypes 27 6 (22) 6 (22) 15 (56)  
    ABC DLBCL 12 (44) 5 (41.5) 5 (41.5) 2 (17)  
    GCB DLBCL 15 (56) 1 (6.5) 1 (6.5) 13 (87) < .001 
Treatment groupn (%)Response, n (%)
P*
CompletePartialNone
All patients 44 8 (18) 7 (16) 29 (66)  
DLBCL (de novo) 31 (70) 7 (23) 6 (19) 18 (58) .63 
Molecular subtypes 27 6 (22) 6 (22) 15 (56)  
    ABC DLBCL 12 (44) 5 (41.5) 5 (41.5) 2 (17)  
    GCB DLBCL 15 (56) 1 (6.5) 1 (6.5) 13 (87) < .001 
*

Fisher exact test.

Excluding primary mediastinal B-cell lymphomas (PMBL).

All de novo DLBCL except PMBL with microarray or immunohistochemical determination of molecular subtype.

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