DA-EPOCH-B toxicity
| Adverse event . | Toxicity grade* . | ||
|---|---|---|---|
| Grade 2, n (%) . | Grade 3, n (%) . | Grade 4, n (%) . | |
| Anemia | 22 (18) | 22 (18) | 2 (2) |
| Neutropenia | 5 (4) | 12 (10) | 39 (32) |
| Thrombocytopenia | 17 (14) | 30 (24) | 19 (15) |
| Platelet transfusion | 13 (11) | 5 (41) | |
| Fever and neutropenia† | 25 (20) | ||
| Nausea/vomiting | 10 (8) | 5 (4) | |
| Diarrhea | 11 (9) | 2 (2) | |
| Motor | 1 (2) | 1 (2) | |
| Sensory | 4 (9) | 6 (14) | |
| Neuropathic pain | 1 (2) | 2 (4) | |
| Autonomic | 1 (2) | 2 (4) | 2 (4) (DLT) |
| Fatigue‡ | 11 (9) | 7 (6) | |
| Adverse event . | Toxicity grade* . | ||
|---|---|---|---|
| Grade 2, n (%) . | Grade 3, n (%) . | Grade 4, n (%) . | |
| Anemia | 22 (18) | 22 (18) | 2 (2) |
| Neutropenia | 5 (4) | 12 (10) | 39 (32) |
| Thrombocytopenia | 17 (14) | 30 (24) | 19 (15) |
| Platelet transfusion | 13 (11) | 5 (41) | |
| Fever and neutropenia† | 25 (20) | ||
| Nausea/vomiting | 10 (8) | 5 (4) | |
| Diarrhea | 11 (9) | 2 (2) | |
| Motor | 1 (2) | 1 (2) | |
| Sensory | 4 (9) | 6 (14) | |
| Neuropathic pain | 1 (2) | 2 (4) | |
| Autonomic | 1 (2) | 2 (4) | 2 (4) (DLT) |
| Fatigue‡ | 11 (9) | 7 (6) | |