Patient characteristics
| Variable . | No PAH . | PAH . | P . |
|---|---|---|---|
| No. | 28 | 27 | |
| Sex, fraction female | 0.61 | 0.56 | NS |
| Age, y | 34 (8) | 42 (11) | < .01 |
| TRV, m/s | 1.4 (0.5) | 3.1 (0.4) | < .001 |
| Leukocytes, ×109/L | 10.6 (3.4) | 11.2 (4.1) | NS |
| Hemoglobin, g/L | 93 (13) | 84 (14) | < .05 |
| Platelets, ×109/L | 415 (149) | 384 (133) | NS |
| Reticulocytes, ×109/L | 314 (314) | 266 (142) | NS |
| Lactate dehydrogenase, IU/L | 334 (115) | 492 (204) | < .001 |
| Alkaline phosphatase, IU/L | 114 (91) | 159 (90) | < .05 |
| Aspartate aminotransferase, IU/L | 41 (21) | 52 (27) | NS |
| Alanine aminotransferase, IU/L | 28 (17) | 29 (14) | NS |
| Bilirubin, total, μM | 46 (22) | 56 (36) | NS |
| Bilirubin, direct, μM | 7 (3) | 12 (12) | < .01 |
| Creatinine, μM | 53 (15) | 61 (23) | < .05 |
| Ferritin, pM | 1723 (2647) | 2916 (3737) | < .05 |
| NT-proBNP, pg/mL | 75 (71) | 1069 (3222) | < .001 |
| Variable . | No PAH . | PAH . | P . |
|---|---|---|---|
| No. | 28 | 27 | |
| Sex, fraction female | 0.61 | 0.56 | NS |
| Age, y | 34 (8) | 42 (11) | < .01 |
| TRV, m/s | 1.4 (0.5) | 3.1 (0.4) | < .001 |
| Leukocytes, ×109/L | 10.6 (3.4) | 11.2 (4.1) | NS |
| Hemoglobin, g/L | 93 (13) | 84 (14) | < .05 |
| Platelets, ×109/L | 415 (149) | 384 (133) | NS |
| Reticulocytes, ×109/L | 314 (314) | 266 (142) | NS |
| Lactate dehydrogenase, IU/L | 334 (115) | 492 (204) | < .001 |
| Alkaline phosphatase, IU/L | 114 (91) | 159 (90) | < .05 |
| Aspartate aminotransferase, IU/L | 41 (21) | 52 (27) | NS |
| Alanine aminotransferase, IU/L | 28 (17) | 29 (14) | NS |
| Bilirubin, total, μM | 46 (22) | 56 (36) | NS |
| Bilirubin, direct, μM | 7 (3) | 12 (12) | < .01 |
| Creatinine, μM | 53 (15) | 61 (23) | < .05 |
| Ferritin, pM | 1723 (2647) | 2916 (3737) | < .05 |
| NT-proBNP, pg/mL | 75 (71) | 1069 (3222) | < .001 |
Values for all continuous variables represent means, with standard deviations indicated in parentheses. Significance was determined by Wilcoxon-Mann-Whitney test, except for sex (χ2 test).
PAH indicates pulmonary arterial hypertension; TRV, tricuspid regurgitant jet velocity; and NT-proBNP, N-terminal pro–brain-type natriuretic hormone.