Table 3 Factors associated with poor... | American Society of Hematology

Table 3

Factors associated with poor immune reconstitution at last follow-up

Variables	Crude OR* (95% CI)	P†
CD4 T-cell count
Host chimerism	5.4 (1.1-27)	.04
Low CD4⁺ T-cell count 1 y after HSCT	15.9 (3.8-66)	< .001
Low CD4⁺ T-cell count 2 y after HSCT	11 (3.2-41)	< .001
Immunoglobulin substitution
Molecular diagnosis		.05
Rag-1/2 deficiency	1
Artemis deficiency	13 (1.2-129)	.03‡
γ c/Jak3 deficiency	12 (1.5-99)	.02‡
Others	1.8 (0.1-32)	.7‡
Host chimerism	5.6 (1.2-86)	.03
Immunoglobulin substitution 2 y after HSCT	22 (5.6-86)	< .001

Variables	Crude OR* (95% CI)	P†
CD4 T-cell count
Host chimerism	5.4 (1.1-27)	.04
Low CD4⁺ T-cell count 1 y after HSCT	15.9 (3.8-66)	< .001
Low CD4⁺ T-cell count 2 y after HSCT	11 (3.2-41)	< .001
Immunoglobulin substitution
Molecular diagnosis		.05
Rag-1/2 deficiency	1
Artemis deficiency	13 (1.2-129)	.03‡
γ c/Jak3 deficiency	12 (1.5-99)	.02‡
Others	1.8 (0.1-32)	.7‡
Host chimerism	5.6 (1.2-86)	.03
Immunoglobulin substitution 2 y after HSCT	22 (5.6-86)	< .001

OR indicates odds ratio; and 95% CI, 95% confidence interval.

Odds ratio calculated with a logistic regression model (with continuous variable of time).

Wald test.

Wald test for each category.