Table 1 Splenic B-cell subsets in p85α... | American Society of Hematology

Table 1

Splenic B-cell subsets in p85α^−/− and Btk^−/− mice

Genotype*	Total, ×10⁶	T1, ×10⁶	T2, ×10⁶	T3, ×10⁶	FO, ×10⁶	MZ, ×10⁶
p85α^+/−, n = 6	88.3	0.92	1.54	2.80	24.1	0.47
p85α^−/−, n = 6	68.0†	0.42‡	0.91§	0.57‡	3.62‡	0.09‡
Btk^+/−, n = 4	67.0	0.69	0.77	0.86
Btk^−/−, n = 4	28.0†	0.63†	0.32†	0.09‡

Genotype*	Total, ×10⁶	T1, ×10⁶	T2, ×10⁶	T3, ×10⁶	FO, ×10⁶	MZ, ×10⁶
p85α^+/−, n = 6	88.3	0.92	1.54	2.80	24.1	0.47
p85α^−/−, n = 6	68.0†	0.42‡	0.91§	0.57‡	3.62‡	0.09‡
Btk^+/−, n = 4	67.0	0.69	0.77	0.86
Btk^−/−, n = 4	28.0†	0.63†	0.32†	0.09‡

Mice are on a BALB/c background (p85α^+/− and p85α^−/− mice) or on a mixed background between C57BL/6 and 129/Sv (Btk^+/− and Btk^−/− mice).

Significance between knockout and control mice was examined by the Mann-Whitney U test: †no significance;

P < .01 from control heterozygous mice;

P < .05 from control heterozygous mice.