Table 4

Front-line treatment of brain parenchyma relapse

TreatmentPatients, no. (%)
Total 113 
Chemotherapy only 52 (46) 
    Methotrexate-based 49 (43) 
    Other chemotherapy* 3 (3) 
Chemotherapy and WBRT 26 (23) 
    Methotrexate-based 22 (19) 
    Other chemotherapy 4 (4) 
WBRT only 34 (30) 
Brain surgery only 1 (1) 
TreatmentPatients, no. (%)
Total 113 
Chemotherapy only 52 (46) 
    Methotrexate-based 49 (43) 
    Other chemotherapy* 3 (3) 
Chemotherapy and WBRT 26 (23) 
    Methotrexate-based 22 (19) 
    Other chemotherapy 4 (4) 
WBRT only 34 (30) 
Brain surgery only 1 (1) 

WBRT indicates whole brain radiotherapy.

*

Other chemotherapies were rituximab (n = 1); rituximab and temozolomide (n = 1); and bleomycin, vincristine, procarbazine, prednisone, dexamethasone, ifosfamide, carboplatin, etoposide (n = 1).

Other chemotherapies were cytarabine (n = 2); vincristine, dexamethasone, cytarabine, cisplatin (n = 1); and cyclophosphamide, thiotepa, etoposide (n = 1).

One patient had brain surgery only and was excluded from the analysis of treatment characteristics.

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