The CD34+lin−CD7− subpopulation contains a high frequency of myelo-erythroid progenitors
| . | % BFU-E . | % CFU mix . | % CFU-GM . | % total CFU . |
|---|---|---|---|---|
| CD34+lin−CD7−, mean ± SE (n = 24) | 0.6 ± 0.2 | 1.1 ± 0.3 | 1.6 ± 0.3 | 3.3 ± 0.6* |
| CD34+lin−CD7intCD10+, mean ± SE (n = 5) | 0 | 0.02 ± 0.02 | 0.02 ± 0.02 | 0.05 ± 0.05 |
| CD34+lin−CD7hi, mean ± SE (n = 12) | 0 | 0 | 0.02 ± 0.01 | 0.02 ± 0.01 |
| . | % BFU-E . | % CFU mix . | % CFU-GM . | % total CFU . |
|---|---|---|---|---|
| CD34+lin−CD7−, mean ± SE (n = 24) | 0.6 ± 0.2 | 1.1 ± 0.3 | 1.6 ± 0.3 | 3.3 ± 0.6* |
| CD34+lin−CD7intCD10+, mean ± SE (n = 5) | 0 | 0.02 ± 0.02 | 0.02 ± 0.02 | 0.05 ± 0.05 |
| CD34+lin−CD7hi, mean ± SE (n = 12) | 0 | 0 | 0.02 ± 0.01 | 0.02 ± 0.01 |
Cells of each immunophenotype were isolated by FACS from fresh thymus and plated in methylcellulose medium.
n indicates number of experiments.
P < .001, significant difference between frequency of total CFU in CD7− and the other two populations.