Cumulative incidence of VTE in acute leukemia
| VTE . | AML, n = 5394 . | ALL, n = 2482 . | ||||
|---|---|---|---|---|---|---|
| Cumulative incidence, no. (%) . | Rate/100 pt years, % . | Death (%) . | Cumulative incidence, no. (%) . | Rate/100 pt years, % . | Death (%) . | |
| Total venous thrombotic events | ||||||
| 0-24 mo | 281 (5.2) | 7.3 | 4251 (78.8) | 113 (4.5) | 3.1 | 864 (34.8) |
| Less than 3 mo | 181 (3.3) | 19.2 | 2319 (43) | 62 (2.5) | 11.1 | 307 (12.4) |
| 3-6 mo | 46 (0.9) | 6.9 | 623 (11.5) | 25 (1) | 3.1 | 99 (4) |
| 6-12 mo | 36 (0.7) | 3.7 | 765 (14.1) | 16 (0.6) | 1.7 | 203 (8.2) |
| 12-24 mo | 18 (0.3) | 1.4 | 544 (11.1) | 10 (0.4) | 0.6 | 255 (10.3) |
| Deep vein thrombosis or pulmonary embolism | ||||||
| 0-24 mo | 195 (3.6) | 5.0 | 92 (3.7) | 2.5 | ||
| Less than 3 mo | 120 (2.2) | 12.7 | 48 (1.9) | 8.6 | ||
| 3-6 mo | 34 (0.6) | 5.1 | 21 (0.8) | 4.1 | ||
| 6-12 mo | 27 (0.5) | 2.8 | 14 (0.6) | 1.5 | ||
| 12-24 mo | 14 (0.3) | 1.1 | 9 (0.4) | 0.5 | ||
| Upper extremity deep vein thrombophlebitis | ||||||
| 0-24 mo | 86 (1.6) | 2.2 | 21 (0.9) | 0.6 | ||
| Less than 3 mo | 61 (1.1) | 6.5 | 14 (0.6) | 2.5 | ||
| 3-6 mo | 12 (0.2) | 1.8 | 4 (0.2) | 0.8 | ||
| 6-12 mo | 9 (0.2) | 0.9 | 2 (0.1) | 0.2 | ||
| 12-24 mo | 4 (0.1) | 0.3 | 1 (0.05) | 0.06 | ||
| VTE . | AML, n = 5394 . | ALL, n = 2482 . | ||||
|---|---|---|---|---|---|---|
| Cumulative incidence, no. (%) . | Rate/100 pt years, % . | Death (%) . | Cumulative incidence, no. (%) . | Rate/100 pt years, % . | Death (%) . | |
| Total venous thrombotic events | ||||||
| 0-24 mo | 281 (5.2) | 7.3 | 4251 (78.8) | 113 (4.5) | 3.1 | 864 (34.8) |
| Less than 3 mo | 181 (3.3) | 19.2 | 2319 (43) | 62 (2.5) | 11.1 | 307 (12.4) |
| 3-6 mo | 46 (0.9) | 6.9 | 623 (11.5) | 25 (1) | 3.1 | 99 (4) |
| 6-12 mo | 36 (0.7) | 3.7 | 765 (14.1) | 16 (0.6) | 1.7 | 203 (8.2) |
| 12-24 mo | 18 (0.3) | 1.4 | 544 (11.1) | 10 (0.4) | 0.6 | 255 (10.3) |
| Deep vein thrombosis or pulmonary embolism | ||||||
| 0-24 mo | 195 (3.6) | 5.0 | 92 (3.7) | 2.5 | ||
| Less than 3 mo | 120 (2.2) | 12.7 | 48 (1.9) | 8.6 | ||
| 3-6 mo | 34 (0.6) | 5.1 | 21 (0.8) | 4.1 | ||
| 6-12 mo | 27 (0.5) | 2.8 | 14 (0.6) | 1.5 | ||
| 12-24 mo | 14 (0.3) | 1.1 | 9 (0.4) | 0.5 | ||
| Upper extremity deep vein thrombophlebitis | ||||||
| 0-24 mo | 86 (1.6) | 2.2 | 21 (0.9) | 0.6 | ||
| Less than 3 mo | 61 (1.1) | 6.5 | 14 (0.6) | 2.5 | ||
| 3-6 mo | 12 (0.2) | 1.8 | 4 (0.2) | 0.8 | ||
| 6-12 mo | 9 (0.2) | 0.9 | 2 (0.1) | 0.2 | ||
| 12-24 mo | 4 (0.1) | 0.3 | 1 (0.05) | 0.06 | ||