Table 2 Interaction of leukocyte and... | American Society of Hematology

Table 2

Interaction of leukocyte and platelet counts at diagnosis (multivariable model)

Interaction	n (%)*	Rate of vascular event (% patients/year)	Low risk† (% patients)	JAK2^V617F‡ (% patients)	RR (P value)
1. WBC less than 11, Plt more than 1000	170 (16)	1.59	95 (56)	35 (26)	1
2. WBC less than 11, Plt less than 1000	644 (62)	2.26	317 (49)	304 (56)	1.92 (.034)
3. WBC more than 11, Plt more than 1000	99 (9)	2.88	41 (41)	40 (61)	2.38 (.026)
4. WBC more than 11, Plt less than 1000	130 (12)	2.95	52 (40)	75 (77)	2.43 (.017)

Interaction	n (%)*	Rate of vascular event (% patients/year)	Low risk† (% patients)	JAK2^V617F‡ (% patients)	RR (P value)
1. WBC less than 11, Plt more than 1000	170 (16)	1.59	95 (56)	35 (26)	1
2. WBC less than 11, Plt less than 1000	644 (62)	2.26	317 (49)	304 (56)	1.92 (.034)
3. WBC more than 11, Plt more than 1000	99 (9)	2.88	41 (41)	40 (61)	2.38 (.026)
4. WBC more than 11, Plt less than 1000	130 (12)	2.95	52 (40)	75 (77)	2.43 (.017)

WBC and Plt counts are ×10⁹/L.

Twenty patients were excluded because of WBC or platelet count data missing at diagnosis.

Age younger than 60 years and no previous thrombosis; untreated (90%).

Percentage calculated on 860 patients evaluated for JAK2^V617F.