Table 1

Enhanced cytotoxicity of NK cells against bortezomib-treated patient MM cells

PatientUntreated lysis plus or minus SD, %Treated lysis plus or minus SD, %Fold increase, no.E/T ratio
Allogenic NK 
    1 13.9 ± 2.8 39.6 ± 3.9 2.8 15:1 
    2 8.6 ± 6.6 22.7 ± 5.1 2.6 14:1 
    3 6.4 ± 3.0 61.5 ± 7.2 9.6 20:1 
    4 4.8 ± 2.7 19.0 ± 1.7 4.0 20:1 
Autologous NK 
    5 2.6 ± 3.7 27.6 ± 4.4 10.6 15:1 
    6 0.2 ± 3.4 45.9 ± 7.7 229.5 9:1 
PatientUntreated lysis plus or minus SD, %Treated lysis plus or minus SD, %Fold increase, no.E/T ratio
Allogenic NK 
    1 13.9 ± 2.8 39.6 ± 3.9 2.8 15:1 
    2 8.6 ± 6.6 22.7 ± 5.1 2.6 14:1 
    3 6.4 ± 3.0 61.5 ± 7.2 9.6 20:1 
    4 4.8 ± 2.7 19.0 ± 1.7 4.0 20:1 
Autologous NK 
    5 2.6 ± 3.7 27.6 ± 4.4 10.6 15:1 
    6 0.2 ± 3.4 45.9 ± 7.7 229.5 9:1 

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