Table 1

Comparison of functions and localization of the 12-kDa and 8-kDa isoforms of p12I

p12I isoform↓ TCR signaling↓ Viral replicationRecruitment to ISLocalization
12 kDa − − − ER 
8 kDa Plasma membrane 
p12I isoform↓ TCR signaling↓ Viral replicationRecruitment to ISLocalization
12 kDa − − − ER 
8 kDa Plasma membrane 

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