Table 3

Multivariate analysis of risk factors

VariableOverall survival
Event-free survival
HR (95% CI)PHR (95% CI)P
WBC at diagnosis, ×109/L (less than 30, n=42; more than 30, n = 36; na = 1) 1.92 (1.02-3.61 .05 1.79 (0.98-3.29) .06 
Prior radiation therapy (yes, n = 13; no, n = 61; na = 5) 1.44 (0.67-3.12) .35 1.35 (0.64-2.86) .43 
Disease status at HCT (CR1, n = 49; beyond CR1, n = 30) 2.14 (1.09-4.15) .03 1.99 (1.06-3.74) .03 
Acute GVHD (yes, n = 26; no, n = 51) 1.77 (0.95-3.32) .07 (1.01-3.36) .05 
VariableOverall survival
Event-free survival
HR (95% CI)PHR (95% CI)P
WBC at diagnosis, ×109/L (less than 30, n=42; more than 30, n = 36; na = 1) 1.92 (1.02-3.61 .05 1.79 (0.98-3.29) .06 
Prior radiation therapy (yes, n = 13; no, n = 61; na = 5) 1.44 (0.67-3.12) .35 1.35 (0.64-2.86) .43 
Disease status at HCT (CR1, n = 49; beyond CR1, n = 30) 2.14 (1.09-4.15) .03 1.99 (1.06-3.74) .03 
Acute GVHD (yes, n = 26; no, n = 51) 1.77 (0.95-3.32) .07 (1.01-3.36) .05 

HR indicates hazard ratio; WBC, white blood cell count; HCT, hematopoietic cell transplantation; and GVHD, graft-versus-host disease.

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