Table 1

Baseline and disease characteristics

No. (%)
Median age, y (range) 57 (18-81) 
Median time from diagnosis of CML, mo 34 
Response to prior interferon alpha therapy  
    Hematologic failure 133 (29) 
    Cytogenetic failure 160 (35) 
    Intolerance 161 (35) 
Chromosomal abnormalities  
    Yes 74 (16) 
    No 363 (80) 
    Missing 17 (4) 
Splenomegaly more than 0 cm below costal margin 82 (18) 
Hemoglobin level less than 100 g/L 30 (7) 
WBC count of 50 × 109/L or more 84 (19) 
Platelet count more than 450 × 109/L 147 (32) 
No. (%)
Median age, y (range) 57 (18-81) 
Median time from diagnosis of CML, mo 34 
Response to prior interferon alpha therapy  
    Hematologic failure 133 (29) 
    Cytogenetic failure 160 (35) 
    Intolerance 161 (35) 
Chromosomal abnormalities  
    Yes 74 (16) 
    No 363 (80) 
    Missing 17 (4) 
Splenomegaly more than 0 cm below costal margin 82 (18) 
Hemoglobin level less than 100 g/L 30 (7) 
WBC count of 50 × 109/L or more 84 (19) 
Platelet count more than 450 × 109/L 147 (32) 

N = 454. Data are number (%) unless otherwise indicated.

WBC indicates white blood cell.

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