Up-regulated genes after coculture of CLL cells with NLCs
| Gene name . | No. of cases with more than 3-fold up-regulation . | Mean up-regulation in 9 samples, fold change . |
|---|---|---|
| CCL4 | 7 | 10.16 |
| TNFRSF17 | 7 | 6.72 |
| EGR3 | 7 | 5.97 |
| CCL3 | 6 | 6.09 |
| PSAT1 | 6 | 4.98 |
| MYCN | 6 | 4.96 |
| EGR2 | 6 | 4.84 |
| KIAA0101 | 6 | 4.39 |
| KMO | 6 | 3.93 |
| FCRL5 | 6 | 3.31 |
| Gene name . | No. of cases with more than 3-fold up-regulation . | Mean up-regulation in 9 samples, fold change . |
|---|---|---|
| CCL4 | 7 | 10.16 |
| TNFRSF17 | 7 | 6.72 |
| EGR3 | 7 | 5.97 |
| CCL3 | 6 | 6.09 |
| PSAT1 | 6 | 4.98 |
| MYCN | 6 | 4.96 |
| EGR2 | 6 | 4.84 |
| KIAA0101 | 6 | 4.39 |
| KMO | 6 | 3.93 |
| FCRL5 | 6 | 3.31 |
This table displays, in descending order, the top 10 genes up-regulated in CLL cells after coculture with NLCs. The left column displays the gene names. The middle column displays the number of CLL paired specimens that displayed a more than 3-fold gene up-regulation (of a total of 9 cases). The right column indicates the mean up-regulation of the genes in all 9 cases.
CCL4 indicates CC chemokine; TNFRSF17, B-cell maturation antigen (BCMA); EGR3, early growth response protein 3 gene; CCL3, CC chemokine; PSAT1, phosphoserine aminotransferase 1; MYCN, N-myc proto-oncogene; EGR2, early growth response protein 2 gene; KIAA0101, uncharacterized gene sequence; KMO, kynurenine 3-hydroxylase; and FCRL5, Fc receptor-like 5.