Frequency of nonspecific promoter polymorphism −386 G > C and frequency of stop codon versus ORF in exon 3 of FCGR2C
| . | Controls . | All ITP . | Adult ITP . | Children ITP . |
|---|---|---|---|---|
| Promotor 2B/C −386 | ||||
| GG | 75 (75) | 68 (58.6) | 25 (56.8) | 43 (59.7) |
| CG | 25 (25) | 47 (40.5) | 18 (40.9) | 29 (40.2) |
| CC | 0 (0) | 1 (0.9)*† | 1 (2.3)†‡ | 0 (0)†§ |
| FCGR2C exon 3 | ||||
| STOP | 6 (6) | 4 (3.4) | 0 (0) | 4 (5.6) |
| STOP/STOP | 66 (66) | 68 (58.6) | 28 (63.6) | 40 (55.6) |
| STOP/STOP/STOP | 10 (10) | 4 (3.4) | 1 (2.3) | 3 (4.2) |
| ORF | 1 (1) | 2 (1.7) | 0 (0) | 2 (2.8) |
| ORF/ORF | 0 (0) | 3 (2.6) | 2 (4.5) | 1 (1.4) |
| ORF/STOP | 16 (16) | 32 (27.6) | 11 (25) | 21 (29.2) |
| ORF/ORF/STOP | 0 (0) | 1 (0.9) | 1 (2.3) | 0 (0) |
| ORF/STOP/STOP | 1 (1) | 2 (1.7)¶‖ | 1 (2.3)§‖ | 1 (1.4)‖# |
| FCGR2C exon 3 (allele frequency) | ||||
| STOP | 186 (91.2) | 189 (81.1) | 73 (80.2) | 116 (81.7) |
| ORF | 18 (8.8) | 44 (18.9)** | 18 (19.8)* | 26 (18.3)* |
| . | Controls . | All ITP . | Adult ITP . | Children ITP . |
|---|---|---|---|---|
| Promotor 2B/C −386 | ||||
| GG | 75 (75) | 68 (58.6) | 25 (56.8) | 43 (59.7) |
| CG | 25 (25) | 47 (40.5) | 18 (40.9) | 29 (40.2) |
| CC | 0 (0) | 1 (0.9)*† | 1 (2.3)†‡ | 0 (0)†§ |
| FCGR2C exon 3 | ||||
| STOP | 6 (6) | 4 (3.4) | 0 (0) | 4 (5.6) |
| STOP/STOP | 66 (66) | 68 (58.6) | 28 (63.6) | 40 (55.6) |
| STOP/STOP/STOP | 10 (10) | 4 (3.4) | 1 (2.3) | 3 (4.2) |
| ORF | 1 (1) | 2 (1.7) | 0 (0) | 2 (2.8) |
| ORF/ORF | 0 (0) | 3 (2.6) | 2 (4.5) | 1 (1.4) |
| ORF/STOP | 16 (16) | 32 (27.6) | 11 (25) | 21 (29.2) |
| ORF/ORF/STOP | 0 (0) | 1 (0.9) | 1 (2.3) | 0 (0) |
| ORF/STOP/STOP | 1 (1) | 2 (1.7)¶‖ | 1 (2.3)§‖ | 1 (1.4)‖# |
| FCGR2C exon 3 (allele frequency) | ||||
| STOP | 186 (91.2) | 189 (81.1) | 73 (80.2) | 116 (81.7) |
| ORF | 18 (8.8) | 44 (18.9)** | 18 (19.8)* | 26 (18.3)* |