Table 1 VWF secretion and retention .... | American Society of Hematology

Table 1

VWF secretion and retention

	VWF secretion, pmol/10⁶ cells per 72 h	VWF retention, % of total/10⁶ cells per 72 h
VWF-CFP wild type	5.8 ± 0.2	27 ± 2
VWF-CFP Arg763Gly	4.4 ± 0.5*	30 ± 2
VWF-CFP Thr791Met	4.1 ± 0.2†	28 ± 1
VWF-CFP Arg816Trp	4.1 ± 0.2†	23 ± 3
VWF-CFP Arg854Gln	3.5 ± 0.1†	27 ± 2
VWF-CFP Cys1060Arg	3.3 ± 0.3†	29 ± 3

	VWF secretion, pmol/10⁶ cells per 72 h	VWF retention, % of total/10⁶ cells per 72 h
VWF-CFP wild type	5.8 ± 0.2	27 ± 2
VWF-CFP Arg763Gly	4.4 ± 0.5*	30 ± 2
VWF-CFP Thr791Met	4.1 ± 0.2†	28 ± 1
VWF-CFP Arg816Trp	4.1 ± 0.2†	23 ± 3
VWF-CFP Arg854Gln	3.5 ± 0.1†	27 ± 2
VWF-CFP Cys1060Arg	3.3 ± 0.3†	29 ± 3

HEK293 cells were transfected using 5 μg plasmid DNA. Conditioned medium and cell lysate were analyzed on VWF levels. Each value represents the mean plus or minus SD of 3 transfections. Statistically significant differences are indicated.

P < .05.

†

P < .001.

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