Risk factors at presentation of primary myelofibrosis selected at the stepwise Cox regression model for significant association with shorter survival*
| Risk factor . | Frequency in the series, % . | Hazard ratio (95% CI) . | z test . | P . |
|---|---|---|---|---|
| Age > 65 y | 44.6 | 1.95 (1.61-2.36) | 6.84 | < .001 |
| Constitutional symptoms | 26.4 | 1.97 (1.62-2.40) | 6.77 | < .001 |
| Hb < 10 g/dL | 35.2 | 2.89 (2.46-3.61) | 11.24 | < .001 |
| WBC count > 25 × 109/L | 9.6 | 2.40 (1.83-3.14) | 6.37 | < .001 |
| Blood blasts > 1% | 36.2 | 1.80 (1.50-2.17) | 6.29 | < .001 |
| Risk factor . | Frequency in the series, % . | Hazard ratio (95% CI) . | z test . | P . |
|---|---|---|---|---|
| Age > 65 y | 44.6 | 1.95 (1.61-2.36) | 6.84 | < .001 |
| Constitutional symptoms | 26.4 | 1.97 (1.62-2.40) | 6.77 | < .001 |
| Hb < 10 g/dL | 35.2 | 2.89 (2.46-3.61) | 11.24 | < .001 |
| WBC count > 25 × 109/L | 9.6 | 2.40 (1.83-3.14) | 6.37 | < .001 |
| Blood blasts > 1% | 36.2 | 1.80 (1.50-2.17) | 6.29 | < .001 |
In 1001 patients with the 5 variables available.